Individual differences associated with treatment adherence and transfer effects following gamified web-based cognitive control training for repetitive negative thinking

Hoorelbeke, Kristof; Vervaeke, Jasmien; Siegle, Greg J.; Baeken, Chris; Koster, Ernst H. W.

doi:10.1016/j.invent.2022.100507

Cited by 8 publications

(14 citation statements)

References 114 publications

(198 reference statements)

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“…Moreover, profiles with greater risk of poor outcomes appeared to benefit more from more intensive treatment and frequent monitoring. Similar results were found in a study in which latent profile analysis was conducted to identify user profiles based on broad indicators of functioning, among which baseline level of cognitive functioning, use of (mal)adaptive emotion regulation strategies, level of internalizing symptomatology, training progress, user experience, and personality factors (Hoorelbeke et al, 2022). In particular, this study identified three user profiles, reflecting low-, moderate-and high-risk for internalizing psychopathology.…”

Section: Treatment Efficacy and Its Moderatorssupporting

confidence: 82%

“…In this context, it has been suggested that a more integrative approach may be required in order to better capture profiles of functioning (Hoorelbeke et al, 2022). For instance, in a study examining subgroups based on baseline patient characteristics, interesting profiles emerged for the treatment and prevention of depression (Saunders et al, 2021).…”

Section: Treatment Efficacy and Its Moderatorsmentioning

confidence: 99%

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Cognitive remediation for depression vulnerability: Current challenges and new directions

Zwalmen

Hoorelbeke²,

Liebaert³

et al. 2022

Front. Psychol.

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It is increasingly acknowledged that cognitive impairment can play an important role in depression vulnerability. Therefore, cognitive remediation strategies, and cognitive control training (CCT) procedures have gained attention in recent years as possible interventions for depression. Recent studies suggest a small to medium effect on indicators of depression vulnerability. Despite initial evidence for the efficacy and effectiveness of CCT, several central questions remain. In this paper we consider the key challenges for the clinical implementation of CCT, including exploration of (1) potential working mechanisms and related to this, moderators of training effects, (2) necessary conditions under which CCT could be optimally administered, such as dose requirements and training schedules, and (3) how CCT could interact with or augment existing treatments of depression. Revisiting the CCT literature, we also reflect upon the possibilities to evolve toward a stratified medicine approach, in which individual differences could be taken into account and used to optimize prevention of depression.

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Section: Treatment Efficacy and Its Moderatorssupporting

confidence: 82%

Section: Treatment Efficacy and Its Moderatorsmentioning

confidence: 99%

Cognitive remediation for depression vulnerability: Current challenges and new directions

Zwalmen

Hoorelbeke²,

Liebaert³

et al. 2022

Front. Psychol.

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“…For these between-subject designs, effect sizes were calculated using post measure means and their standard deviations, with the esc_mean_sd function from the esc package in R (Lüdecke, 2019). For four studies, where no suitable control group was available (Brunoni et al, 2014;Sommer & Plewnia, 2021;Vanderhasselt et al, 2015;Hoorelbeke, Vervaeke, et al, 2022), individual participant data was requested from the authors to calculate pre-post correlations (see supplementary table A2). Effect sizes were then calculated from prepost measures, taking correlations into account (Harrer et al, 2021).…”

Section: Discussionmentioning

confidence: 99%

“…Of all 19 included studies, 18 were randomized controlled trials (RCT). One study was categorized as a single-arm trial (Hoorelbeke, Vervaeke, et al, 2022). The search and selection process is depicted in a PRISMA flow diagram (see Fig.…”

Section: Study Selection and Data Extractionmentioning

confidence: 99%

“…Finally, Hoorelbeke, Van den Bergh, et al, 2022 Across all incorporated studies, around 72% of participants were female, with a mean age of 37.9 (SD = 12.7). The sample sizes which were used for the calculation of effect sizes ranged from n = 9 (Segrave et al, 2014) to n = 213 (Hoorelbeke, Vervaeke, et al, 2022), with a median of n = 49 (IQR = 50). Of the 19 included studies, 7 (36.8%) focused on a major depressed population, 4 (21.1%) on remitted depressed patients, 5 on an at-risk population (26.3%) and 3 examined effects of aPASAT training in a healthy sample (15.8%).…”

Section: Study Characteristicsmentioning

confidence: 99%

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Treatment response following adaptive PASAT training for depression vulnerability: A systematic review and meta-analysis

Zwalmen¹,

Liebaert²,

Hoorelbeke³

et al. 2022

Preprint

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BackgroundIn recent years, cognitive control training (CCT) has gained momentum as an intervention to remediate cognitive impairments and decrease depressive symptoms. One promising operationalization to train cognitive control is the adaptive Paced Auditory Serial Addition Task (aPASAT). In this systematic review and meta-analysis of aPASAT training, the efficacy of the intervention and potential moderators were examined.MethodThe PsycINFO, MEDLINE, Embase, Web of Science and Cochrane Library electronic databases were searched for studies examining aPASAT training for depressive symptomatology or rumination.ResultsNineteen studies (n=1257) were included, comprising of depressed patients, remitted depressed patients, at-risk, and healthy participants. We found small significant effects directly after training for both depressive symptomatology and rumination, with similar effect sizes at follow- up. Subgroup analyses suggest a significantly higher mean effect of aPASAT training in non- healthy populations for rumination immediately following training, but not for depressive symptomatology. The amount of training sessions did not moderate effects of CCT.ConclusionsaPASAT has a small but significant effect on depressive symptoms, with direct effects immediately after training, as well as sustained long-term effects. It is currently unclear how many sessions are required for sustained effects due to heterogeneity in training dosage and absence of sufficient trials. Our results suggest that aPASAT training may be most effective for at-risk, remitted- and clinically depressed populations. The effect sizes resulting from this meta- analysis could be used to adequately power future research, which could investigate a dose- response relationship and examine potential treatment gains when combining CCT with other antidepressant interventions.

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Can Students Learn to Optimize Their Need-Based Experiences and Mental Health During a Stressful Period? Testing a Need-Crafting Intervention in Higher Education

van den Bogaard,

Soenens,

Brenning

et al. 2024

J Happiness Stud

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Individual differences associated with treatment adherence and transfer effects following gamified web-based cognitive control training for repetitive negative thinking

Cited by 8 publications

References 114 publications

Cognitive remediation for depression vulnerability: Current challenges and new directions

Cognitive remediation for depression vulnerability: Current challenges and new directions

Treatment response following adaptive PASAT training for depression vulnerability: A systematic review and meta-analysis

Can Students Learn to Optimize Their Need-Based Experiences and Mental Health During a Stressful Period? Testing a Need-Crafting Intervention in Higher Education

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