Indium‐Mediated Allenylation of Aldehydes and Its Application in Carbohydrate Chemistry: Efficient Synthesis of D‐Ribulose and 1‐Deoxy‐D‐ribulose (Eur. J. Org. Chem. 9/2011)

Abstract

The cover picture shows the application of an indium‐mediated allenylation reaction of aldehydes using 4‐bromo‐2‐butyn‐1‐ols to generate α‐hydroxyacetyl anion equivalents. This carbon chain elongation method allows the straightforward synthesis of various substituted dihydroxyacetone fragments, as well as pentuloses and derivatives thereof. Details are discussed in the article by W. Schmid et al. on p. 1645 ff. The background shows the lovely coast of Mayo, Ireland. The authors express their gratitude to Prof. Karl Grubmayr on the occasion of his 60th birthday.