Indium-111 Platelet Scintigraphy in a Patient with Chronic Disseminated Intravascular Coagulation

Abstract

The authors describe a relation between the in vivo localized consumption of In-111 platelets and results of laboratory tests in a 82-year-old man with an aortic graft prosthesis who had chronic disseminated intravascular coagulation. In-111 platelets accumulated markedly over the abdominal aortic graft with a shortened platelet survival time and reflected changes in hematologic studies, which showed low platelet counts and a high concentration of fibrinogen degradation products in the plasma. If a strong clinical likelihood of local disseminated intravascular coagulation exists, then In-111 platelets may be valuable in localizing the focus of platelet consumption.

Blood Platelet Accumulation in a Dacron Graft Implanted in a Patient with Abdominal Aorta Aneurysm: Quantitative Scintigraphic Assessment Using Indium-111 Labeled Platelets - Case Report*

“…after AAA surgical repair was not accompanied by any clinical symptoms. However, the local activation of coagulation can always be transformed into life-threatening DIC, which has been reported in several AAA patients following vascular graft implantation (16,17).…”