A method for the regioselective 1,2-arylboration of 1,3-butadiene, a feedstock chemical, is reported. The reactions result in the formation of products that can be easily elaborated to other structures. The mechanistic details of this process are also discussed. Scheme 1. Copper/palladium-catalyzed arylboration of 1,3-dienes. Scheme 2. Mechanistic analysis of arylboration of butadiene.Communication Isr. J. Chem. 2020, 60, 394 -397 Scheme 4. Mechanistic analysis of arylboration of butadiene. Scheme 5. Representative functionalizations of an arylboration product.