Indirect Determination of Ranitidine Hydrochloride Using a Chloride Ion Selective Electrode

Abstract

A simple, rapid, and reliable potentiometric method is described for determination of ranitidine hydrochloride in pharmaceutical formulations. Experiments were performed to determine the suitability of using a chloride-ion selective electrode for the indirect estimation of ranitidine hydrochloride. The precision and accuracy of the potentiometric method were determined. We found that they not differ significantly. The advantage of the proposed method is the fact that it can be applied without filtration of the drug sample before analysis.

Thermodynamic Study of Thermal Decomposition of Ranitidine by HPTLC

“…Scientists examined its bioavailability, distribution and concentration in various biological fluids. [1][2][3][4][5][6][7][8][9][10][11] Different types of pharmaceutical preparation [10][11][12][13][14][15][16][17][18][19][20][21] were also examined. Literature does not include various publications about mobile phase selection of ranitidine separation and products of its thermal decomposition.…”