Indirect bright light improves circadian rest-activity rhythm disturbances in demented patients

Someren, Eus J.W. Van; Kessler, Abraham R.; Mirmiran, M.; Swaab, Dick F.

doi:10.1016/s0006-3223(97)89928-3

Cited by 381 publications

(305 citation statements)

References 37 publications

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“…If the ability of short wavelength light to phase shift circadian rhythms is also reduced in the elderly (and this is likely on the basis of the present results), this may have important practical implications. For example, appropriate lighting adjustments may need to be made to hospitalised and housebound elderly who may not be exposed to sufficient amount of illumination (Campbell et al, 1988;Van Someren et al, 1997;Monk et al, 2000). Furthermore, elderly shift workers may need more short wavelength light of a higher intensity than younger colleagues in order to hasten adaptation to a new shift schedule.…”

Section: Discussionmentioning

confidence: 99%

Light-induced melatonin suppression: age-related reduction in response to short wavelength light

Herljevic

Middleton

Thapan

et al. 2005

Experimental Gerontology

143

103

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Section: Discussionmentioning

confidence: 99%

Light-induced melatonin suppression: age-related reduction in response to short wavelength light

Herljevic

Middleton

Thapan

et al. 2005

Experimental Gerontology

143

103

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“…Van Someren et al (80) first reported on the potential therapeutic benefit of increasing incident illumination in care settings. Increasing light exposure of dementia patients does not impact on depression ratings, although there are suggestions that individual cases might benefit (81).…”

Section: Chronotherapeutics In Admentioning

confidence: 99%

The Circadian System in Alzheimer’s Disease: Disturbances, Mechanisms, and Opportunities

Coogan

Schutová

Husung

et al. 2013

Biological Psychiatry

146

131

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Alzheimer's disease (AD) is a devastating neurodegenerative condition associated with severe cognitive and behavioral impairments. Circadian rhythms are recurring cycles that display periods of approximately 24 hours and are driven by an endogenous circadian timekeeping system centered on the suprachiasmatic nucleus of the hypothalamus. We review the compelling evidence that circadian rhythms are significantly disturbed in AD and that such disturbance is of significant clinical importance in terms of behavioral symptoms. We also detail findings from neuropathological studies of brain areas associated with the circadian system in postmortem studies, the use of animal models of AD in the investigation of circadian processes, and the evidence that chronotherapeutic approaches aimed at bolstering weakened circadian rhythms in AD produce beneficial outcomes. We argue that further investigation in such areas is warranted and highlight areas for future research that might prove fruitful in ultimately providing new treatment options for this most serious and intractable of conditions.

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“…Natural light in patient care areas reduced agitation in elderly patients, decreased length of stay, lessened the need for pain medication, and reduced depression. [27][28][29][30][31][32][33] Researchers 34 reported that the cost of an inefficient system for navigation in a major regional hospital was more than $220 000 per year or $448 per bed. Much of this cost involved 4500 hours of hospital staff other than information staff giving directions.…”

Section: Patients and Their Families Weigh In On Evidence-based Hospimentioning

confidence: 99%

Patients and Their Families Weigh in on Evidence-Based Hospital Design

Trochelman

Albert

Spence

et al. 2012

Critical Care Nurse

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to design and build health care facilities founded on research or the best available information, ensuring that the relatively permanent physical environment facilitates the delivery of quality care, thereby improving patients' outcomes and safety. 2 Review of the Literature on EBD in Critical and Acute CareSubstantial support exists for the view that a health care structure itself affects quality of care, patients' safety and satisfaction, as well as staff satisfaction and service efficacy. 3 In a report to the Center for Health Design funded by the Robert Wood Johnson Foundation, Ulrich and associates 4 identified more than 600 studies that link hospital design with clinical outcomes. In recent years, evidence-based design (EBD) has become a more pronounced guiding principle in health care. The concept of EBD is BACKGROUND In 2 landmark publications, the Institute of Medicine reported on significant deficiencies in our current health care system. In response, an area of research examining the role of the physical environment in influencing outcomes for patients and staff gained momentum. The concept of evidence-based design has evolved, and the development of structural guidelines for new hospital construction was instituted by the American Institute of Architects in 2006.OBJECTIVE To determine perceptions of patients and their families of evidence-based design features in a new heart center.METHODS Hospitalized patients and their families, most of whom were in intensive care and step-down units, were surveyed and data from the Hospital Consumer Assessment of Healthcare Providers and Systems were reviewed to determine perceptions of evidence-based design features incorporated into a new heart center and to assess patients' satisfaction with the environment. RESULTS Responses were reviewed and categorized descriptively. Five general environment topics of focus emerged: privacy, space, noise, light, and overall atmosphere. Characteristics perceived as being dissatisfying and satisfying are discussed.CONCLUSIONS Critical care nurses must be aware of the current need to recognize how much the physical environment influences care delivery and take steps to maximize patients' safety, satisfaction, and quality of care. This article has been designated for CE credit. A closed-book, multiple-choice examination follows this article, which tests your knowledge of the following objectives:1. Discuss the concept of evidence-based design in health care environments 2. Identify evidence-based design features associated with improved patient care 3. Recognize the role of physical environment in influencing patient outcomes

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Indirect bright light improves circadian rest-activity rhythm disturbances in demented patients

Cited by 381 publications

References 37 publications

Light-induced melatonin suppression: age-related reduction in response to short wavelength light

Light-induced melatonin suppression: age-related reduction in response to short wavelength light

The Circadian System in Alzheimer’s Disease: Disturbances, Mechanisms, and Opportunities

Patients and Their Families Weigh in on Evidence-Based Hospital Design

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