Indirect Associations of Anxiety Sensitivity with Tobacco, Alcohol, and Other Drug Use Problems Through Emotional Disorder Symptoms in Adolescents

Guillot, Casey R.; Blackledge, Sabrina; Douglas, Megan; Cloutier, Renee M.; Liautaud, Madalyn M.; Pang, Raina D.; Kirkpatrick, Matthew G.; Leventhal, Adam M.

doi:10.1080/08964289.2019.1573797

Cited by 10 publications

(14 citation statements)

References 71 publications

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“…Notably, prior research has associated AS both with SU coping expectancies and motives (i.e., expecting a substance to reduce NA if used and using a substance for the purpose of reducing NA) in regard to smoking, drinking, and cannabis use (DeMartini & Carey, 2011; Guillot et al, 2019), and previous studies in African American samples have associated AS with depression and anxiety symptoms (Carter et al, 2001; Talkovsky & Norton, 2015) and depression and anxiety symptoms with SU (Bares & Andrade, 2012; Clark, 2014; Repetto et al, 2005). Similarly, the current study associated AS with dysphoria (depression/anxiety) symptoms in preliminary correlation analyses and further associated AS and dysphoria symptoms with several SU variables in primary analyses.…”

Section: Discussionmentioning

confidence: 99%

“…In particular, AS has been associated with both SU coping expectancies and motives (i.e., both expecting a substance to reduce NA if used and explicitly reporting the reason for using a substance is to reduce NA, respectively) in regard to cigarette smoking and alcohol and cannabis use (DeMartini & Carey, 2011; Guillot et al, 2019; Guillot, Blumenthal, Zvolensky, & Schmidt, 2018; Guillot, Leventhal, Raines, Zvolensky, & Schmidt, 2016). AS additionally has been associated with problems related to the use of various substances, including tobacco, alcohol, and cannabis (Guillot et al, 2019; Guillot et al, 2018). More specifically in regard to cigarette smokers, AS has been prospectively associated with more intense tobacco withdrawal and higher risk of smoking lapse and relapse (Bakhshaie et al, 2018).…”

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confidence: 99%

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Anxiety sensitivity in relation to cigarette smoking and other substance use in African American smokers.

Kelly

Guillot

Quinn

et al. 2020

Psychology of Addictive Behaviors

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Anxiety sensitivity (AS)—fearfulness of anxiety symptoms—has been implicated in the etiology of emotional disorders (e.g., depressive and anxiety disorders) and linked to cigarette smoking and other substance use (SU). However, studies examining AS in relation to SU primarily have been conducted with racially/ethnically heterogeneous or mostly European American samples. Hence, this cross-sectional study involving secondary analysis of baseline data focused on investigating associations of AS with cigarette smoking and other SU in a sample of 630 non-treatment-seeking African American smokers (37.3% female; M age = 49.6 years; M cigarettes smoked per day = 15.4). After screening out individuals with non-nicotine substance dependence, participants reported their demographics, AS, dysphoria symptoms (i.e., depression and anxiety symptoms), and SU. In regression analyses controlling for dysphoria symptoms, age, education level, income level, and years of regular smoking, AS was positively associated with tobacco withdrawal severity (β = .12, p = .007), overall smoking motives (β = .17, p < .001), alcohol use problems (β = .12, p = .005), and other (non-nicotine, nonalcohol) SU problems (β = .16, p < .001). Though lacking the passage of time between assessments needed to provide strong evidence of mediation, unplanned analyses further revealed indirect associations of AS with several SU variables through dysphoria symptoms. Current findings are consistent with those found in prior samples and suggest that AS is similarly related to SU in African Americans, who may benefit from interventions that have been helpful in improving AS, dysphoria symptoms, and SU in other groups.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Anxiety sensitivity in relation to cigarette smoking and other substance use in African American smokers.

Kelly

Guillot

Quinn

et al. 2020

Psychology of Addictive Behaviors

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“…Consequently, psychosocial maladjustment linked to low peer status and lack of social acceptance alongside high levels of impulsivity and behavioral disinhibition may leave obese adolescents struggling to cope adaptively and lead to an increase in maladaptive coping behaviors like substance use. Past studies have shown adolescents experiencing anxiety and depressive symptoms are at greater risk of substance use initiation and increased use (Anderson, Ramo, & Brown, 2006; Cloutier, Blumenthal, Trim, Douglas, & Anderson, 2019; Guillot et al., 2020; Hussong, Ennett, Cox, & Haroon, 2017; Wilkinson, Halpern, & Herring, 2016). Studies focused exclusively on obese adolescents are scarce, but these studies do suggest internalizing symptoms may inform the relationship between obesity and substance use (Farhat, 2015).…”

Section: Pathways and Processes Underlying Obesity To Substance Use I...mentioning

confidence: 99%

Weighing the Risk: Developmental Pathways and Processes Underlying Obesity to Substance Use in Adolescence

Lanza

2021

J of Research on Adolesc

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Research on co‐occurring obesity and substance use in adolescence has grown substantially in the past decade, but questions on the pathways and processes underlying co‐occurrence remain. This review first synthesizes empirical findings on the relationship between obesity and substance use (e.g., alcohol, cannabis, tobacco use). Multidisciplinary theoretical frameworks referencing behavioral medicine, neuroscience, psychology, and public health are then used to inform an interdisciplinary, conceptual model focused on pathways and processes by which obesity increases risk of substance use. Recommendations for future research underscore the importance of prospective studies that encompass multiple domains of development. Recommendations for practice include family‐based interventions that promote adaptive self‐regulation, targeted antibullying or victimization interventions, and increased attention by health professionals on risky behavior associated with adolescent obesity.

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“…In addition to considering AS and substance use from a general negative reinforcement (e.g., NA reduction) perspective, McNally (1996, p. 222) proposed a more specific hypothesis pertaining to autonomic arousal, in which he stated that high AS “ought to be associated with abuse of substances that reduce arousal (e.g., benzodiazepines, alcohol) but not with substances that increase arousal (e.g., cocaine, amphetamine).” In accord with McNally’s (1996) hypothesis, AS consistently has not been associated with illicit stimulant use among adolescents (Carey, 2020; Castellanos-Ryan et al, 2013; Krank et al, 2011; Stewart et al, 2021), while AS consistently has been associated with sedative/tranquilizer (e.g., benzodiazepine) use among adolescents (Carey, 2020; Stewart et al, 2021). Regarding other substances, however, some studies of adolescents have found that AS is associated with alcohol, cigarette, e-cigarette, cannabis, and opioid use (Carey, 2020; Guillot et al, 2020; Knapp et al, 2021; Paulus et al, 2021), whereas others have not found that AS is associated with these forms of substance use (Bartel et al, 2018; Castellanos-Ryan et al, 2013; Morgenstern et al, 2018; Stewart et al, 2021).…”

mentioning

confidence: 99%

“…Importantly, the mixed findings from adolescents may be due in part to differences in AS assessment. To be more specific, the Childhood Anxiety Sensitivity Index (CASI; Silverman et al, 1991) was used in the studies that associated AS with alcohol, cigarette, e-cigarette, cannabis, and opioid use (Carey, 2020; Guillot et al, 2020; Knapp et al, 2021; Paulus et al, 2021), whereas the Substance Use Risk Profile Scale (SURPS) was used in the studies that did not associate AS with these forms of substance use (Bartel et al, 2018; Castellanos-Ryan et al, 2013; Morgenstern et al, 2018; Stewart et al, 2021). Furthermore, the SURPS has been used to assess adolescent AS in relation to substance use more frequently than the CASI (Bartel et al, 2018), and this is especially relevant given that the validity of the SURPS has been called into question (Blanchard et al, 2020) and because the SURPS–AS measure mostly indexes the physical concerns aspect of AS (i.e., perceiving anxiety-related physical sensations as dangerous; Bartel et al, 2018).…”

mentioning

confidence: 99%

Longitudinal associations between anxiety sensitivity and substance use in adolescents: Mediation by depressive affect.

Guillot,

Pang,

Vilches

et al. 2024

Experimental and Clinical Psychopharmacology

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Though anxiety sensitivity (AS)—fear of anxiety-related experiences—is primarily tied to anxiety vulnerability, AS has also been prospectively associated with general negative affect and depression. Furthermore, depression has been longitudinally associated with different forms of substance use, and some AS subfactors (e.g., cognitive concerns) have been associated more consistently with depression and substance use than others. However, no previous study has investigated if longitudinal associations of AS with substance use may be mediated by depression or whether aspects of AS may be prospectively associated with substance use among adolescents. Hence, the present study tested depressive affect (the negative affective aspect of depression) as a prospective mediator of AS associations with substance use and examined longitudinal AS subfactor associations with substance use and problems. High school 9th graders (N = 2,877; Mage = 14.1 years; 55.3% female) completed self-report measures at baseline and at 6 months and 1 year later. Depressive affect mediated AS associations with subsequent alcohol, cigarette, electronic cigarette, cannabis, benzodiazepine, and opioid use. Also, AS cognitive and social concerns (vs. physical concerns) were more consistently associated with later depressive affect and substance use and problems. Current findings suggest that adolescents high in anxiety sensitivity tend to prospectively experience greater depressive affect, which in turn is related to a higher likelihood of engaging in several different forms of substance use. Thus, it is possible that interventions which target AS (particularly AS cognitive concerns) may help to treat or prevent depression and substance use among adolescents.

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Indirect Associations of Anxiety Sensitivity with Tobacco, Alcohol, and Other Drug Use Problems Through Emotional Disorder Symptoms in Adolescents

Cited by 10 publications

References 71 publications

Anxiety sensitivity in relation to cigarette smoking and other substance use in African American smokers.

Anxiety sensitivity in relation to cigarette smoking and other substance use in African American smokers.

Weighing the Risk: Developmental Pathways and Processes Underlying Obesity to Substance Use in Adolescence

Longitudinal associations between anxiety sensitivity and substance use in adolescents: Mediation by depressive affect.

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