Abstract:Background Patients presenting with head and neck squamous cell
carcinoma of unknown primary (HNSCCUP) remain challenging clinical
scenarios as large variation exists in practices used to locate the
primary. Objective To perform a systematic review of the literature and
offer recommendations for oropharyngeal biopsies in HNSCCUP. Method
Pubmed, Medline and Embase were searched to identify studies from
inception to October 2021. The Preferred Reporting Items for Systematic
Reviews and Meta-analyses (PRISMA) gui… Show more
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