Indications and results of videocapillaroscopy in clinical practice

Gallucci, Fernando; Russo, Ricardo; Buono, Russell J.; Acampora, R; Madrid, E; Uomo, Generoso

doi:10.2478/v10039-008-0038-4

Cited by 70 publications

(52 citation statements)

References 35 publications

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“…This pattern was also observed in diseases such as dermatomyositis and presclerodermic Raynaud's phenomenon 15 . These patients had also decrease of blood flow speed 14 . More recently, this method has been used to evaluate microcirculation in extra-rheumatic diseases such as arterial hypertension, diabetes mellitus, Crohn's disease and psoriasis.…”

Section: Discussionmentioning

confidence: 99%

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Endotelium in Turner syndrome with capillaroscopy

Coelho¹,

Guimarães²,

Fernandes³

2011

J. vasc. bras.

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Objective: The aim of this study was to assess the endothelium function in patients with Turner syndrome using videocapillaroscopy and to compare the results with healthy control. Methods: Subjects and controls were studied in a temperature-controlled room, 20 days after no nailfold manipulations. The capillaries were visualized by a microscope connected to a television and a computer. The test of post-occlusive reactive hyperemia was performed using a sphygmomanometer attached to the fourth left finger, 20mmHg above maximum arterial pressure during 1 minute, and the following patterns were studied: area of transverse segment, maximal post-ischemia area and time to reach maximal post-ischemia area. Results: The value of measure of transverse segment projected area , the maximal postischemia area of hand nailfold capillary loops using computerized videophotometry and the time to reach maximal post ischemia area were studied in 40 patients with Turner syndrome and 26 healthy women controls of comparable age (20±7.5 versus 18±8.1 years old; p=0.57). There were differences between transverse segment area (706.8±139.1 versus 548.8±117.2; p=0.001). Maximal post-ischemia area (891.3±226.1 versus 643.5±134.3; p=0.001) and the time to reach it (10.8±4.3 versus 5.5±2.5; p=0.001) were different between patients and controls. Conclusions: Changes of capillary response to ischemia could be observed in patients with Turner syndrome using videocapillaroscopy when they were compared to a healthy control group.Keywords: Turner syndrome; microscopic angioscopy; endothelium. ResumoObjetivos: O objetivo deste estudo foi avaliar a função endotelial de pacientes com síndrome de Turner, utilizando a videocapilaroscopia e comparar os resultados com grupo controle saudável. Métodos: Pacientes e controles foram estudados em sala com temperatura controlada, após 20 dias, sem a manipulação das cutículas. Os capilares foram visualizados por microscópio conectado a televisão e computador. O teste de hiperemia reativa pós-oclusiva foi realizado utilizando-se esfigmomanômetro fixado no quarto quirodáctilo da mão esquerda, 20mmHg acima da pressão arterial máxima durante 1 minuto, e os seguintes parâmetros foram estudados: área do segmento transverso, área máxima pós-hiperemia e tempo para alcançar a área máxima pós-hiperemia. Resultados: O valor da área do segmento transverso, área máxima pós-hiperemia dos capilares da região da mão usando-se a videocapilaroscopia computadorizada e o tempo para alcançar a área pós-hiperemia foram estudadas em 40 pacientes com síndrome de Turner e 26 controles do sexo feminino pareados para idade (20±7,5 versus 18±8,1 anos; p=0,57). Houve diferenças nos grupos quanto à área do segmento transverso (706,8±139,1 versus 548,8±117,2; p=0,001). A área máxima pós-hiperemia (891,3±226,1 versus 643,5±134,3; p=0,001) e o tempo para alcançá-la (10,8±4,3 versus 5,5±2,5; p=0,001) foram significativamente diferentes entre pacientes e controles. Conclusão: Houve alterações na resposta do capilar à isquemia em pacientes...

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Section: Discussionmentioning

confidence: 99%

“…Nailfold videocapillaroscopy is one of the best noninvasive imaging techniques to evaluate microcirculation in vivo and has been shown to be applicable to the study of many rheumatic diseases, specially in systemic sclerosis 14 .…”

Section: Discussionmentioning

confidence: 99%

Endotelium in Turner syndrome with capillaroscopy

Coelho¹,

Guimarães²,

Fernandes³

2011

J. vasc. bras.

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“…Endothelial cells play an important role in pathogenesis of psoriasis as immune-mediated inflammatory features and papillary dermis have multiple blood vessels, as well as they show microvascular changes such as decreased capillary density and avascular areas. Additionally, NVC can provide some information regarding morphostructural changes of capillaries including tortuosity, elongation, dilatation, and crosslinked [11][12][13][14][15]. Several studies with capillaroscopy have been performed in patients with psoriasis, with either nail or joint involvement [16][17][18][19].…”

Section: Introductionmentioning

confidence: 99%

The microvascular and morphostructural changes of nails in psoriatic patients with nail disease; a link between ultrasound and videocapillaroscopy findings in the nailfold

Üreyen¹,

Kara²,

Ertürk³

et al. 2018

Med Ultrason

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Objective: The objective of this study is to evaluate the link between nail fold vessel resistive index (NVRI) measured by ultrasound (US) and capillary loops diameters measured using nailfold videocapillarascopy (NVC), and to assess the morphological appearance of the nail bed in patients with psoriatic nail disease (PND) as compared with healthy controls (HCs).Material and methods: This study was conducted in patients with PND and HCs. General demographic data were collected and clinical assessments were performed for all subjects. The nail plate thickness (NPT) was measured on gray scale using US. The NVRI was measured using color Doppler (CD) US. The measurements of the apical, arterial, venous limb diameters and morpho-structural changes (tortuous, cross-linked capillaries) were assessed using NVC.Results: Thirty-four patients with PND and 15 HCs were enrolled in this study. The two groups were matched for age and body mass index (BMI). Patients with PND had higher NPT and NVRI in comparison with HCs [(20 (17-23) vs 14 (14-15), p<0.001), (0.55 (0.51-0.61) vs 0.43 (0.38-0.49), p<0.001), respectively]. A higher proportion of patients with PND had tortuous capillaries than HCs (62% and 20% respectively, p=0.005). The mean NVRI was higher in patients with PND who had tortuous capillaries than patients who did not have tortuous capillaries (0.58 (0.7) and 0.52 (0.09), respectively p=0.033).Conclusion: Microvascular changes can be detected easily using non-invasive methods such as US and NVC. These methods can provide an objective data to better assess PND.

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“…Rheumatic diseases such as Raynaud's disease and systemic sclerosis are investigated frequently by nail-fold capillaroscopy (Grassi and Angelis 2007). Recently nail-fold capillaroscopy has been applied to diseases other than rheumatism for example diabetes, hypertension, acromegaly, and psoriasis (Gallucci et al 2008). In severe diabetes, the capillaroscopy show dilated capillaries.…”

Section: Introductionmentioning

confidence: 99%

A computerized system of nail-fold capillaroscopy for dry eye disease diagnosis

Hou

Huang

Wang

et al. 2012

Multidim Syst Sign Process

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Nail-fold Capillaroscopy is a convenient and non-invasive tool to evaluate peripheral circulation. Rheumatic diseases such as Raynaud's disease and systemic sclerosis are investigated mostly by nail-fold capillaroscopy. However, it has not been used popularly due to the lack of golden standard in both measurement procedure and objective quantity analysis. This study proposes a computerized system of nail-fold capillaroscopy (CNC). CNC includes standard measurement procedures and three criterions of microcirculation which are capillary density, capillary width and blood flow velocity. CNC is applied to the images of 36 normal subjects and seven patients of dry eye disease (DED). We found density and width of afferent capillary were the better parameters to identify DED ( p < 0.05). CNC could be a good auxiliary diagnostic tool for DED.

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Indications and results of videocapillaroscopy in clinical practice

Cited by 70 publications

References 35 publications

Endotelium in Turner syndrome with capillaroscopy

Endotelium in Turner syndrome with capillaroscopy

The microvascular and morphostructural changes of nails in psoriatic patients with nail disease; a link between ultrasound and videocapillaroscopy findings in the nailfold

A computerized system of nail-fold capillaroscopy for dry eye disease diagnosis

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