Index-based calculation or Transient Elastography to assess the degree of hepatic steatosis and fibrosis

Xie, Ruijie; Zhang, Ya

doi:10.1016/j.tjnut.2022.10.015

Cited by 18 publications

(14 citation statements)

References 5 publications

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“…Percentages were used to characterize categorical variables which were compared by c 2 testing. To evaluate the relationship between smoking status and infertility, multivariable logistic regression was performed and the odds ratio (OR) values and 95% confidence intervals (95%CI) were calculated (28)(29)(30)(31)(32). Three models were built for the multivariate test.…”

Section: Discussionmentioning

confidence: 99%

Associations between smoking status and infertility: a cross-sectional analysis among USA women aged 18-45 years

2023

Front. Endocrinol.

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BackgroundAlthough many studies have proven the harmful effects of smoking on human health, the associations between smoking status and infertility are limited in large epidemiologic studies. We aimed to investigate the associations between smoking status and infertility among child-bearing women in the United States of America (USA).MethodsA total of 3,665 female participants (aged 18-45) from the National Health and Nutrition Examination Survey (NHANES) (2013-2018) were included in this analysis. All data were survey-weighted, and corresponding logistic regression models were performed to investigate the associations between smoking status and infertility.ResultsIn a fully adjusted model, the risk of infertility was found to be increased by 41.8% among current smokers compared to never smokers (95% CI: 1.044-1.926, P=0.025). In the subgroup analysis, the odds ratios (95% CI) of the risk of infertility for current smokers were 2.352 (1.018-5.435) in the unadjusted model for Mexican American, 3.675 (1.531-8.820) in the unadjusted model but 2.162 (0.946-4.942) in fully adjusted model for people aged 25-31, 2.201 (1.097-4.418) in the unadjusted model but 0.837 (0.435-1.612) in fully adjusted model for people aged 32-38.ConclusionCurrent smokers was associated with a higher risk of infertility. The underlying mechanism of these correlations still needs more research. Our findings indicated that quitting smoking may serve as a simple index to reduce the risk of infertility.

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Section: Discussionmentioning

confidence: 99%

Associations between smoking status and infertility: a cross-sectional analysis among USA women aged 18-45 years

2023

Front. Endocrinol.

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“…Our study has some limitations. First, due to the design of the cross-sectional study, we were unable to determine the causal relationship between PIR and degree of hepatic steatosis ( 48 , 49 ). In addition, because the PIR is linked to a large number of variables, we were unable to include all covariates that had a potential impact on, which may lead to incomplete accuracy of the results.…”

Section: Discussionmentioning

confidence: 99%

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confidence: 99%

Association of family income to poverty ratio and vibration-controlled transient elastography quantified degree of hepatic steatosis in U.S. adolescents

et al. 2023

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IntroductionInequality in socioeconomic status plays an important role in the prevalence of metabolic diseases in adolescents. The purpose of this study was to explore the association between family income and the degree of hepatic steatosis quantified by vibration-controlled transient elastography (VCTE) among U.S. adolescents.MethodsThis cross-sectional study included two cycles of the National Health and Nutrition Examination Survey (NHANES) 2017-2020. Multivariate linear regression and smoothing curve fitting were used to investigate the linear and nonlinear relationship between PIR and hepatic steatosis, respectively. Subgroup analysis and interaction tests were used to test whether this relationship was stable across groups.ResultsOf the 1,574 adolescent participants, 456 lived in poor households and 307 lived in wealthy households. After adjusting for all covariates, PIR (Ratio of family income to poverty) was significantly negatively associated with the degree of hepatic steatosis [-4.78 (-7.39, -2.17)], and this remained stable after converting PIR to a categorical variable. In addition, this significant negative association was more pronounced in women [-7.62 (-11.38, -3.87)], non-Hispanic blacks [-7.19 (-14.43, 0.06)], Mexican Americans [-6.80 (-13.63, 0.03)], and participants with BMI >30 cm2 [-10.83 (-19.70, -1.96)].ConclusionsPIR was significantly and negatively associated with the degree of hepatic steatosis in US adolescents. Additional prospective studies are needed to confirm our findings.

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“…The Chi-square test and t-test were used to assess the demographic characteristics of the participants by BMI subgroups. Multivariate logistic regression analyses were used to investigate the association between SES, BMI and lumbar BMD (20)(21)(22). The potential mediated effect of BMI on the association between SES and lumbar BMD was estimated by parallel mediator analysis.…”

Section: Discussionmentioning

confidence: 99%

BMI, socioeconomic status, and bone mineral density in U.S. adults: Mediation analysis in the NHANES

Zhang

Tan²,

Tan³

2023

Front. Nutr.

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IntroductionThe mechanism by which socioeconomic status (SES) affects bone mineral density (BMD) remains unknown, and body mass index (BMI) may be a potential mediator. The purpose of this study was to investigate whether BMI mediates the relationship between SES [education level and poverty income ratio (PIR)] and lumbar BMD and the proportion it mediates.MethodsThis study included a total of 11,075 adults from the National Health and Nutrition Examination Survey (NHANES). Lumbar BMD was measured at the lumbar spine by dual-energy X-ray absorptiometry (DXA). Multivariate linear regression and smoothing curve fitting were used to investigate the relationship between SES and lumbar BMD. Mediator analysis was used to investigate the proportion of BMI mediating the association between SES and BMD.ResultsIn the fully adjusted model, there was a positive correlation between SES and BMD (education level: β = 0.025, 95% CI: 0.005, 0.045; PIR: β = 0.007, 95% CI: 0.002, 0.011). Mediation analysis showed that BMI mediated the relationship between PIR, education level, and lumbar BMD with a range of mediation proportions from 13.33 to 18.20%.ConclusionBMI partially mediated the positive association between SES and BMD, and this association may be largely mediated by factors other than BMI.

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Index-based calculation or Transient Elastography to assess the degree of hepatic steatosis and fibrosis

Cited by 18 publications

References 5 publications

Associations between smoking status and infertility: a cross-sectional analysis among USA women aged 18-45 years

Associations between smoking status and infertility: a cross-sectional analysis among USA women aged 18-45 years

Association of family income to poverty ratio and vibration-controlled transient elastography quantified degree of hepatic steatosis in U.S. adolescents

BMI, socioeconomic status, and bone mineral density in U.S. adults: Mediation analysis in the NHANES

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