Indeterminate Dendritic Cell Tumor

Histiocytic tumors are a highly heterogeneous group of diseases, with Langerhans cell histiocytosis occupying the main place among it. Despite the rare frequency of occurrence, long-term analysis of clinical, morpho-immunological and molecular-biological features has allowed the development of effective treatment protocols (especially in the pediatric cohort of patients). In addition to Langerhans cell histiocytosis, the histiocytic tumors group includes rare and casuistic variants, which include histiocytic sarcoma, Langerhans cell sarcoma, indeterminate dendritic cell tumor, interdigitating dendritic cell sarcoma, follicular dendritic cell sarcoma, and fibroblastic reticular cell tumor. The incidence of certain nosological variants is several cases per hundreds of millions of the population. Not surprisingly, the diagnostic criteria for this group of tumors need to be clarified, as do the therapeutic approaches. This review presents current data on rare histiocytic tumors, clinical features as well as morphological and immunobiological characteristics of the tumor substrate. The results of modern surgical and therapeutic treatment approaches are presented.

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Rare variants of histiocytic tumors: peculiarities of diagnosis and choice of treatment (literature review)

Валиев

Gurieva

Pavlovskaya

2022

Onkogematologiâ

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Indeterminate Dendritic Cell Tumor

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Rare variants of histiocytic tumors: peculiarities of diagnosis and choice of treatment (literature review)

Rare variants of histiocytic tumors: peculiarities of diagnosis and choice of treatment (literature review)

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