Indeterminate colitis and other relative controindications to restorative proctocolectomy: Immediate and long-term results

Montesani, C; Pronio, Annamaria; Santella, S; Brini, C; Chessa, A; Damato, AN; Ribotta, G

doi:10.1016/s1590-8658(00)80251-0

Cited by 1 publication

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“…However, compared to the abdominal approaches for rectal cancer, taTME arises new specific complications, including rectal or vaginal perforation [25] , bladder injury, and the injury of the urethra and urethral sphincter [26] , which not No matter the taTME surgery or the IORT, we should pay attention to the anorectal function, especially the bowel frequency and fecal incontinence. TaTME transanal approach may bring injury to the intersphincteric resection [27] and the radiotherapy may induce the fibrosis around rectum affecting the compliance of rectum [28] . Both of them may lead to the low anterior resection syndrome (LARS), a complex of symptoms consisting of incontinence for flatus and /or feces, constipation, urgency, and bowel movements [29] .…”

Section: Discussionmentioning

confidence: 99%

TaTME Combined with IORT for the Treatment of Locally Advanced Rectal Cancer：A case report

Guo

Wang

Zhao

et al. 2021

Preprint

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Transanal total mesorectal excision (taTME) which aims to achieve more accurately complete resection of distal mesorectum has arouse much more attention worldwide. TaTME can significantly improve the local control (LC) and overall survival (OS) of the patients with locally advanced rectal cancer. Intraoperative radiotherapy (IORT), also as a emerging treatment method for locally advanced tumors, can lead to the potential for dose escalation, reduce overall treatment time, and increase patient convenience. Our study firstly combined taTME and IORT for the treatment of locally advanced rectal cancer. The tumor involved 60 mm rectal wall and located 30 mm from anal margin. TaTME and IORT were successfully achieved in this patient. There was no obvious complications occurred, including the anastomotic fistula. The patient recovered well and further systematic systematic chemotherapy and radiotherapy were suggested. We conclude that taTME with low-energy X-rays IORT may not only benefit the circumferential resection margin (CRM) but also improve the local control (LC) for the patient with locally advanced rectal cancer.

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