Independent lesions of fixed drug eruption caused by trimethoprim-sulfamethoxazole and tenoxicam in the same patient: A rare case of polysensitivity

Özkaya‐Bayazit, Esen

doi:10.1016/j.jaad.2004.01.062

Cited by 19 publications

(14 citation statements)

References 17 publications

(13 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…FDE in any individual patient may be the result of ingestion of only a single medication, but cross‐reactivity with related drugs is well‐described 17 . Less common, but also described, are patients who exhibit FDE to multiple unrelated drugs 18,19 …”

Section: Discussionmentioning

confidence: 99%

Vulval fixed drug eruption due to paracetamol

Drummond

Fischer

2009

Aust J Dermatology

View full text Add to dashboard Cite

Paracetamol is a readily available non-prescription analgesic. Fixed drug eruption (FDE) is a wellreported side effect of paracetamol, usually the classic, pigmenting type. In women, it may present as a chronic, erosive vulvitis. We describe a case of FDE due to paracetamol presenting as a chronic erosive vulvitis in an older woman taking multiple medications. Diagnosis was delayed because paracetamol is available without prescription, taken intermittently and may be omitted from the clinical history. Cessation of paracetamol led to prompt resolution of symptoms. Consideration should be given to paracetamol as a cause of FDE presenting as a chronic erosive vulvitis.

show abstract

Section: Discussionmentioning

confidence: 99%

Vulval fixed drug eruption due to paracetamol

Drummond

Fischer

2009

Aust J Dermatology

View full text Add to dashboard Cite

show abstract

“…FDEs usually have a single causative drug, and polysensitivity involving two or more drugs is rare 7. Piroxicam and cotrimoxazole, tenoxicam and trimethoprim-sulfamethoxazole, and various anticonvulsants have been reported to cause polysensitive FDEs 7-9…”

Section: Discussionmentioning

confidence: 99%

A Case of Fixed Drug Eruption Due to Doxycycline and Erythromycin Present in Food

Lim

Kim

Jin

et al. 2013

Allergy Asthma Immunol Res

View full text Add to dashboard Cite

A fixed drug eruption (FDE) is not difficult to diagnose, given its clinical characteristics. However, the causative agent can be difficult to identify, particularly when the patient denies ingestion of any drugs. To the best of our knowledge, we present herein the first reported case of an FDE caused by antibiotics taken in food; doxycycline and erythromycin contained in pork and fish. A 57-year-old female experienced repeated episodes of well-demarcated erythematous patches covering her entire body. She denied taking any medications, but she thought that the lesions appeared after consuming pork and/or fish. An oral provocation test showed positive results for doxycycline and erythromycin, commonly used antibiotics in live-stock farming and in the fishing industry. Because of the antibiotics' thermostability, cooking does not guarantee the elimination of residual drugs. From the patient's history, we concluded that doxycycline and erythromycin contained in the pork and fish that she ate were the cause of the FDE.

show abstract

“…However, our case seems to be distinct from either the case of cross‐sensitivity or the case of polysensitivity. In the most cases of FDE by multiple drugs, each drug reactivates different lesions separately (6), whereas in this cases, there is the particularly that the association of the drugs reactive all lesions at the same time. The etiopathogenic mechanism of FDE due to a drug combination is not yet understood.…”

Section: Discussionmentioning

confidence: 99%

Multiple fixed drug eruption due to drug combination

Hara

2005

Contact Dermatitis

View full text Add to dashboard Cite

We report the case of a multiple fixed drug eruption (FDE) after taking 1 g of PL and 100 mg of levofloxacin (Cravit) at the same time. Patch tests with PL alone, levofloxacin alone and the combination of PL and levofloxacin were all negative on the involved and uninvolved sites. Lymphocytic stimulation tests were also negative for PL alone, levofloxacin alone and the combination of PL and levofloxacin. Oral provocation tests with PL alone or levofloxacin alone produced no reactivation. However, we could provoke multiple erythematous plaques on the involved areas by taking a 1/10th dose of the combination of PL and levofloxacin at the same time. Drug eruption due to a drug combination appears to be very rare. This is the first case of multiple FDE caused by taking PL-levofloxacin combination.

show abstract

Independent lesions of fixed drug eruption caused by trimethoprim-sulfamethoxazole and tenoxicam in the same patient: A rare case of polysensitivity

Cited by 19 publications

References 17 publications

Vulval fixed drug eruption due to paracetamol

Vulval fixed drug eruption due to paracetamol

A Case of Fixed Drug Eruption Due to Doxycycline and Erythromycin Present in Food

Multiple fixed drug eruption due to drug combination

Contact Info

Product

Resources

About