Independent Functions of Viral Protein and Nucleic Acid in Growth of Bacteriophage

Hershey, A. D.; Chase, Martha

doi:10.1007/978-3-662-47150-0_3

Cited by 53 publications

(59 citation statements)

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“…Watson and Crick solved the basic structure of DNA (Watson and Crick 1953). The association of DNA with the genetic material had been made ten years before by Avery and coworkers (Avery et al 1944) and had been confirmed by Hershey andChase in 1952 (Hershey andChase 1952). The notion that the physical base of inheritance resides in DNA paved the way to several important findings, such as those of Jacob and Monod (Jacob and Monod 1961), and became widely accepted over the '70s.…”

Section: Genetic-biochemical Conception Had Its Turning Point Towardsmentioning

confidence: 90%

What is a Gene? A Two Sided View

et al. 2016

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The need to account for all currently available experimental observations \ud \ud concerning the gene nature, has reshaped the concept of gene turning it from the \ud \ud essentially mechanistic unit, predominant during the '70s, into a quite abstract \ud \ud open and generalized entity, whose contour appears less defined as compared to the \ud \ud past. Here we propose the essence of the gene to be considered double faced. In \ud \ud this respect genotypic and phenotypic entities of a gene would coexist and mix \ud \ud reciprocally. This harmonizes present knowledge with current definitions and \ud \ud predisposes for remodelling of our thinking as a consequence of future discoveries. \ud \ud A two sided view of the gene also allows to combine the genetic and epigenetic \ud \ud aspects in a unique solution, being structural and functional at the same time and \ud \ud simultaneously able to include the different levels in an overlapping unicum

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Section: Genetic-biochemical Conception Had Its Turning Point Towardsmentioning

confidence: 90%

What is a Gene? A Two Sided View

et al. 2016

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“…En 1865 Gregorio Mendel, demostró que existían rasgos que se transmitían de padres a hijos, hoy conocidos como genes (Mendel, 1866); a finales 1920, Frederick Griffith, halló el principio transformador (Griffith, 1928); luego conocido como ADN. Posteriormente en los trabajos con bacteriófagos concluyeron que el ADN era la molécula de la herencia (Hershey & Chase, 1952); los estudios de difracción de rayos X permitieron confirmar la propuesta teórica del modelo de la doble hélice del ADN (Franklin, 1953); y la ley de Chargaff demostró que la cantidad de Adenina (A) es igual a la de Timina (T), y la de Guanina (G) a la de Citosina(C) (Chargaff, 1951).…”

Section: Introductionunclassified

Textos escolares de ciencias: la transposición didáctica y la lingüística sistémico-funcional del modelo de la doble hélice del ADN

2016

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El texto escolar es el resultado de los procesos de didactización de los saberes para la escuela moderna, en ellos subyacen prescripciones curriculares, ideologías y discursos; que ejercen control en el proceso de aprendizaje, influyen en el comportamiento de las personas y contribuyen con la calidad de la educación. Con el fin de determinar la comunicación de los saberes en los libros de texto de ciencias naturales de grado noveno, se hizo un análisis de contenido sobre el tema del modelo de la doble hélice del ácido desoxirribonucleico (ADN), en cuanto a contenidos y como estos son expresados, vistos desde las teorías de la Transposición Didáctica (TD) y la Lingüística Sistémico Funcional (LSF). En los tres textos analizados, se hallaron errores de TD respecto al modelo descrito originalmente y en cuanto a la LSF predominan los procesos relacionales sobre los materiales característicos de las ciencias naturales, la mayoría de verbos fueron usados en presente simple, existen metáforas-nominalizaciones; que conllevan a un discurso de 1.Artículo de investigación científica y tecnológica-USTA Doctorado Educación.

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“…Experiments byHershey and Chase ([1952]) used radioactive isotopes to separately label DNA and protein. They showed that bacteriophages, in order to replicate themselves, insert DNA but not protein into cells.…”

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confidence: 99%

Presume It Not: True Causes in the Search for the Basis of Heredity

Novick

Scholl

2020

The British Journal for the Philosophy of Science

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Kyle Stanford has recently given substance to the problem of unconceived alternatives, which challenges the reliability of inference to the best explanation (IBE) in remote domains of nature. Conjoined with the view that IBE is the central inferential tool at our disposal in investigating these domains, the problem of unconceived alternatives leads to scientific anti-realism. We argue that, at least within the biological community, scientists are now and have long been aware of the dangers of IBE. We re-analyze the nineteenth-century study of inheritance and development (Stanford's case study) and extend it into the twentieth century, focusing in particular on both classical Mendelian genetics and the studies by Avery et al. on the chemical nature of the hereditary substance. Our extended case studies show the preference of the biological community for a different methodological standard: the vera causa ideal, which requires that purported causes be shown on non-explanatory grounds to exist and be competent to produce their effects. On this basis, we defend a prospective realism about the biological sciences.

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Independent Functions of Viral Protein and Nucleic Acid in Growth of Bacteriophage

Cited by 53 publications

References 0 publications

What is a Gene? A Two Sided View

What is a Gene? A Two Sided View

Textos escolares de ciencias: la transposición didáctica y la lingüística sistémico-funcional del modelo de la doble hélice del ADN

Presume It Not: True Causes in the Search for the Basis of Heredity

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