Incumplimiento del tratamiento antibiótico sistémico prescrito en servicios de urgencias de Atención Primaria (Estudio INCUMAT)

Vega-Cubillo, E.M.; Andrés-Carreira, J.M.; Cirillo-Ibargüen, S.; Manzanares-Arnaiz, C.; Moreno-Moreno, G.; Redondo‐Figuero, Carlos

doi:10.1016/j.semerg.2016.03.004

Cited by 4 publications

(5 citation statements)

References 22 publications

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“…In our study, 38% of patients showed a lack of adherence when assessed using Morisky-Green test. Our results are in line with those observed in the Incumat study, 23 carried out in two emergency rooms in Spain. In this study, a lack of adherence of 33% was recorded, using the same questionnaire.…”

Section: Discussionsupporting

confidence: 92%

“…Forgetfulness was the main reason for non-adherence to treatment (24%), a result that matches with what authors described in the Incumat study. 23 Kardas and collaborators published a meta-analysis where they reviewed 2848 articles and observed that 38% of patients were nonadherent, higher percentages were reached when adherence was assessed by other methods rather than Morisky-Green. 24 Furthermore, if adherence to antibiotic treatment is assessed by an objective monitoring technique that records each opening of the medication package (MEMS), only 30% of patients had excellent adherence, which could be due to a trend of overestimate adherence when a self-reported method is used.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…In line with our results, the research group lead by Vega-Cubillo, found significant differences in adherence related to patient sex, where women were more adherent to their antibiotic treatments than men. 23 Among the results obtained, we found that more than a third of the patients underused antibiotic treatment and despite this, they resolved their health problem. Numerous studies in recent years, such as the one by the group led by Spellberg, have shown that short-term antimicrobial therapies (3 to 5 days) are at least as effective as those lasting 7 to 14 days.…”

mentioning

confidence: 80%

“…The large sample size compared with other studies previously conducted in Spain 23,45 and the participation of several pharmacists from different pharmacy offices are among the main strengths of the study, as they increase the generalizability of the findings. Since all questionnaires were completed verbally, which also allowed the inclusion of patients with limited reading and writing skills, thus reducing the risk of selection bias.…”

Section: Strengths and Limitationsmentioning

confidence: 97%

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Study of the Drivers of Inappropriate Use of Antibiotics in Community Pharmacy: Request for Antibiotics Without a Prescription, Degree of Adherence to Treatment and Correct Recycling of Leftover Treatment

Zarauz¹,

Zafrilla²,

Ballester³

et al. 2022

IDR

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Introduction The WHO considered antibiotic resistance as 1 of the 10 greatest threats to global health in 2019. The inappropriate and indiscriminate use of antibiotics, together with the lack of new therapeutic alternatives, may eradicate their effectiveness in the closest future. Objective The general objective is to analyze the different causes attributable to patients, providers and pharmacists that could be drivers of irrational use of antibiotics, and responsible for the appearance of bacterial resistance, in community pharmacies. To this end, the different processes or indicators were studied: patients’ requests of antibiotics at the pharmacy, their degree of adherence, satisfaction with the prescribed treatment and antibiotics’ surplus recycling. Methods This study was observational, descriptive, and cross-sectional, carried out in 2 pharmacy offices, including 333 participants. At the time of dispensing, first phase, surveys to collect patients’, providers’ and pharmacists’ data were carried out over the counter. The second phase, with the aim of checking adherence, degree of satisfaction and recycling. Results There were 333 requests for antibiotic regardless prescription availability, 17% of the patients requested an antibiotic without having one. 38% of patients did not have full adherence to antibiotics. Exploring non-adherence reasons, 24% forgot to take the treatment, 2% experienced adverse effects; 8% improved infection symptoms and 21% had problems to follow schedule. Regarding the recycling habits, 57% of patients had leftover treatments at home, but only 11% recycled it. 10% of medical prescriptions were forced by the patient, and significant gender differences were observed in adherence and knowledge of treatment. Conclusion The results of this study suggested that there may be a significant level of antibiotic inappropriate use locally, potentially related to patients’ sex, finding significant deficiencies in prescription by doctors, in the dispensing act carried out in community pharmacies, and finally in patient compliance with treatment.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 80%

Section: Strengths and Limitationsmentioning

confidence: 97%

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