Incremental value of myocardial viability for prediction of long-term prognosis in surgically revascularized patients with left ventricular dysfunction

Sawada, S. G.; Bapat, Aneesh; Vaz, Dev

doi:10.1016/j.accreview.2004.03.030

Cited by 15 publications

(22 citation statements)

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“…From this perspective, presence of nonrevascularized territories could contribute to false positive results and to decreased specificity of test, limiting in turn its prognostic interpretation [27]. Furthermore, recent studies [28,29] suggest that ischaemia at echo-stress is not the main determinant of prognosis in patients with ischaemic left ventricular dysfunction whereas myocardium viability is a major contributor and a strong predictor of cardiac events. Given these findings, we focused on ischemia as prognostic stratifier only in patients with preserved or mild impaired left ventricular function.…”

Section: Discussionmentioning

confidence: 98%

Dipyridamole stress echocardiography stratifies outcomes of asymptomatic patients with recent myocardial revascularization

Rossi

Moccetti

Faletra

et al. 2007

Int J Cardiovasc Imaging

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Section: Discussionmentioning

confidence: 98%

Dipyridamole stress echocardiography stratifies outcomes of asymptomatic patients with recent myocardial revascularization

Rossi

Moccetti

Faletra

et al. 2007

Int J Cardiovasc Imaging

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“…Ultimately, the shortfalls of the wall motion score index may also be its advantage, and its use underscores the value of the present study (10). Whereas other more esoteric measures of myocardial viability may have appeal, calculating low-dose dobutamine wall motion score index is feasible and reproducible.…”

Section: See Page 2099mentioning

confidence: 79%

“…In this issue of the Journal, Sawada et al (10) address the incremental value of myocardial viability detected using low-dose dobutamine stress echocardiography on the prediction of prognosis five years after surgical revascularization. They found that prognosis after coronary bypass surgery is related to the presence and extent of viable myocardium, and that the data contributed by low-dose dobutamine stress echocardiography are complementary to clinical information and data derived from the baseline echocardiogram.…”

Section: See Page 2099mentioning

confidence: 98%

Viability, prognosis, revascularization, and pascal**Editorials published in the Journal of the American College of Cardiologyreflect the views of the authors and do not necessarily represent the views of JACCor the American College of Cardiology.

Bach

2003

Journal of the American College of Cardiology

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The presence and severity of ischemic left ventricular (LV) systolic dysfunction is an important predictor of prognosis. There are ample data demonstrating that for patients with coronary artery disease and ischemic LV dysfunction, revascularization is associated with a better prognosis compared with medical therapy alone. In addition, varying degrees of recovery of LV dysfunction can be observed after revascularization. To predict which patients will benefit most from surgical revascularization (and possibly which patients may not benefit at all), attempts have been made to prospectively assess the extent of myocardium that is dysfunctional but viable. However, the published literature on testing for myocardial viability is complicated, with conclusions that are sometimes contradictory. To a large degree, this is due to the disparate clinical scenarios in which myocardial viability is evaluated, the different noninvasive techniques used for its assessment, the vagaries of revascularization, and the variety of outcomes measured. See page 2099

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“…Since the report by Allman et al [1••], other studies have shown concordant results [26][27][28], that in patients with ischemic cardiomyopathy, the presence of myocardial viability consistently predicts improved survival following revascularization.…”

Section: Viability and Survivalmentioning

confidence: 85%

Prognostic and therapeutic implications of myocardial viability in patients with heart failure

Udelson

2004

Curr Cardiol Rep

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Substantial progress has been made in understanding the pathophysiology of regional and global left ventricular (LV) dysfunction and the states of hibernation and stunning in patients with heart failure. The clinical literature on the use of noninvasive imaging to assess myocardial viability has evolved from predicting improvement in regional LV function to predicting patient-related outcomes, including heart failure symptom improvement and survival after revascularization. A substantial body of observational cohort data demonstrates that mortality risk is high in patients with coronary artery disease and LV dysfunction who have substantial viable myocardium, and that risk is reduced by revascularization. Thus, noninvasive imaging of myocardial ischemia and viability can provide important prognostic information in patients with heart failure and LV dysfunction, and provide a signal of the potential benefit of revascularization.

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Incremental value of myocardial viability for prediction of long-term prognosis in surgically revascularized patients with left ventricular dysfunction

Cited by 15 publications

References 0 publications

Dipyridamole stress echocardiography stratifies outcomes of asymptomatic patients with recent myocardial revascularization

Dipyridamole stress echocardiography stratifies outcomes of asymptomatic patients with recent myocardial revascularization

Viability, prognosis, revascularization, and pascal**Editorials published in the Journal of the American College of Cardiologyreflect the views of the authors and do not necessarily represent the views of JACCor the American College of Cardiology.

Prognostic and therapeutic implications of myocardial viability in patients with heart failure

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