2020
DOI: 10.1016/j.jaccao.2020.05.012
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Incremental Value of Global Longitudinal Strain for Predicting Survival in Patients With Advanced AL Amyloidosis

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Cited by 36 publications
(24 citation statements)
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“…801 Additionally, GLS ≥ −15% may serve as an independent prognostic factor of poor overall survival in patients with AL-CA. 802 CMR with LGE and parametric imaging has emerged as a new non-invasive gold-standard for diagnosis (Figure 43). 803,804 Nuclear scintigraphy can differentiate transthyretin amyloidosis from AL-CA supported by the presence of monoclonal protein.…”
Section: Amyloid Light-chain Cardiac Amyloidosismentioning
confidence: 99%
“…801 Additionally, GLS ≥ −15% may serve as an independent prognostic factor of poor overall survival in patients with AL-CA. 802 CMR with LGE and parametric imaging has emerged as a new non-invasive gold-standard for diagnosis (Figure 43). 803,804 Nuclear scintigraphy can differentiate transthyretin amyloidosis from AL-CA supported by the presence of monoclonal protein.…”
Section: Amyloid Light-chain Cardiac Amyloidosismentioning
confidence: 99%
“…In one study on patients in advanced disease stages, stroke volume was superior even to strain. 9 This is not surprising if we consider that a fixed stroke volume indicates an advanced restrictive cardiomyopathy, with cardiac output relying mostly on heart rate. 4 , 5 Overall, the characterization of LV strain in AL-CA cannot ignore the assessment of its diagnostic and prognostic value during the different stages of the natural history of this condition.…”
Section: Why Has Ls Become So Important To Characterize Cardiac Involvement In Patients With Amyloidosis? What Is the Added Value Of Ls Bmentioning
confidence: 99%
“…2 The same observation had already been reported in at least two other studies. 8 , 9 Conversely, LVEF was reported to be a poor parameter to diagnose AL-CA, being reduced only in late disease stages. 10 LVEF was also a worse predictor of outcome than the myocardial contraction fraction (MCF), defined as the ratio between stroke volume and myocardial volume, reflecting the characteristic discrepancy between LV mass and contractility in CA.…”
Section: Why Has Ls Become So Important To Characterize Cardiac Involvement In Patients With Amyloidosis? What Is the Added Value Of Ls Bmentioning
confidence: 99%
“…Improving endurance is an important goal for treatment and prevention. Resilience is a structure based on the approach based on strengths and indicates the ability of people to cope with problems and risks [9]. In other words, resilience positively adapts to adverse conditions [10].…”
Section: Introductionmentioning
confidence: 99%