Abstract:Natriuretic peptides (NP) are recognized as the most powerful predictors of adverse outcomes in heart failure (HF). We hypothesized that a measure of functional limitation, as assessed by six-minute walking test (6MWT), would improve the accuracy of a prognostic model incorporating a NP. We studied the prognostic value of severe functional impairment (SFI), defined as the inability to perform a 6MWT or a distance walked during a 6MWT <300 m, in 1696 patients with HF admitted to cardiac rehabilitation. The p… Show more
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