Incremental Cost-Effectiveness of Surgical vs. Percutaneous Treatment of Patent Ductus Arteriosus with the Amplatzer™ Duct Occluder in Children: A Systematic Review

Costa, Rodrigo Nieckel da; Ribeiro, Marcelo Silva; Silva, André Ferreira da; Ribeiro, Rodrigo Antonini; Berwanger, Otávio; Biasi, Alexandre; Penna, Helio; Polanczyk, Carísi Anne; Queiroga, Marcelo; Pedra, Carlos Augusto Cardoso

doi:10.1016/s2214-1235(15)30012-0

Cited by 1 publication

(2 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our study, the CE ratio and the ICER were calculated under the following assumptions: the life expectancy of patients with successfully treated PDA is equal to that of the general population; this life expectancy is earned, regardless of the method employed for PDA closure, provided there is no significant residual shunt, similar to the assumptions of Costa et al . [ 1 ] Furthermore, the CE ratio and the ICER were calculated again considering the complications as factors affecting the quality of well-being (QWB) of the patients in the short-term to calculate the QALY gained. Values for the QWB were obtained from the QWB scores for PDA closure by Gray and Weinstein.…”

Section: Methodsmentioning

confidence: 99%

“…Currently, medical cost-effectiveness (CE) studies integrate the cost of treatment and measurements of changes in health-related quality of life after medical intervention and years of life (YOL) gained to estimate the cost of a quality-adjusted life-year (QALY). [ 1 ] Over the past four decades, a number of coils/devices have been used for the percutaneous closure of patent ductus arteriosus (PDA)[ 2 ] with satisfactory results and minimal complications. [ 3 ] To date, the most efficacious and cost effective closure device has not been determined.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Cost-effectiveness analysis of different devices used for the closure of small-to-medium-sized patent ductus arteriosus in pediatric patients

et al. 2017

View full text Add to dashboard Cite

Aims:In this study, we examined the differences in cost and effectiveness of various devices used for the closure of small to medium sized patent ductus arteriosus (PDA).Setting and Design:We retrospectively studied 116 patients who underwent closure of small PDAs between January 2010 and January 2015.Subjects and Methods:Three types of devices were used: the Amplatzer duct occluder (ADO) II, the cook detachable coil and the Nit Occlud coil (NOC). Immediate and late complications were recorded and patients were followed up for 3 months after the procedure.Statistical Methods:All statistical calculations were performed using Statistical Package for the Social Science software. P <0.05 were considered significant.Results:We successfully deployed ADO II devices in 33 out of 35 cases, cook detachable coils in 36 out of 40 cases and NOCs in 38 out of 41 cases. In the remaining nine cases, the first device was unsuitable or embolized and required retrieval and replacement with another device. Eleven patients (9.5%) developed vascular complications and required anticoagulation therapy. Patients who had hemolysis or vascular complications remained longer in the intensive care unit, with consequently higher total cost (P = 0.016). Also, the need for a second device increased the cost per patient.Conclusions:The cook detachable coil is the most cost-effective device for closure of small-to medium-sized PDAs. Calculations of the incremental cost-effectiveness. (ICE) revealed that the Cook detachable coil had less ICE than the ADO II and NOC. The NOC was more effective with fewer complications.

show abstract

Section: Methodsmentioning

confidence: 99%