2020
DOI: 10.1016/j.jtcvs.2019.09.080
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Increasing the United States heart transplant donor pool with donation after circulatory death

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Cited by 68 publications
(37 citation statements)
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“…The shortage of organs for transplantation has been well reported, and numerous efforts to expand the donor pool are underway including utilization of marginal function organs, donation after circulatory death, organs from high-risk patients, and advancement of organ preservation technology. [1][2][3][4] Ex vivo organ perfusion has been an exciting development in combating some of these problems allowing for procurement teams to travel further to obtain suitable organs and allow for utilization of organs that would otherwise be high-risk with standard preservation techniques. 5,6 In this report by Medressova et al, 7 they detail the long-term (3-year) outcomes of a patient who underwent orthotopic heart transplantation utilizing normothermic ex vivo perfusion with the Organ Care System (OCS) from TransMedics Inc.…”
Section: Commentarymentioning
confidence: 99%
“…The shortage of organs for transplantation has been well reported, and numerous efforts to expand the donor pool are underway including utilization of marginal function organs, donation after circulatory death, organs from high-risk patients, and advancement of organ preservation technology. [1][2][3][4] Ex vivo organ perfusion has been an exciting development in combating some of these problems allowing for procurement teams to travel further to obtain suitable organs and allow for utilization of organs that would otherwise be high-risk with standard preservation techniques. 5,6 In this report by Medressova et al, 7 they detail the long-term (3-year) outcomes of a patient who underwent orthotopic heart transplantation utilizing normothermic ex vivo perfusion with the Organ Care System (OCS) from TransMedics Inc.…”
Section: Commentarymentioning
confidence: 99%
“…In contrast, in lung transplantation [17], the INSPIRE trial demonstrated a reduction of primary graft dysfunction in the OCS study arm [18,19]. In nations with the ability to DCD hearts, the use of OCS also allowed for the initiation of DCD heart transplantation programs [20][21][22][23][24][25].…”
Section: Introductionmentioning
confidence: 99%
“…Recently, the adoption of hearts from donation after circulatory death (DCD) has been considered as a promising approach to expanding the donor pool ( Smith et al, 2019 ). DCD heart transplantation has the potential to significantly increase transplant activity by 30% in the United States ( Jawitz et al, 2020 ) and 48% in the United Kingdom ( Messer et al, 2020 ), and will result in a substantial decrease in waiting list mortality. Furthermore, DCD heart transplantation provides comparable 30-day or 1-year postoperative survival in comparison with traditional donation after brain death (DBD) heart transplantation ( Messer et al, 2017 , 2020 ).…”
Section: Introductionmentioning
confidence: 99%