Increasing the management options for early pregnancy loss: the economics of miscarriage

Management of first-trimester miscarriage: a systematic review and network meta-analysis

“…While EXP is arguably cheaper than other treatment options, the higher probability of complications might increase its associated cost. There is a need for a comprehensive economic evaluation with extended decision models to accommodate for the effectiveness of all available treatment options and potential adverse outcomes (Strand, 2015). Comprehensive policymaking including all available treatment options could offer better value for money and facilitate higher patient satisfaction (Dalton et al, 2015;Molnar et al, 2000;Wallace et al, 2010) (Supplementary Figure S2).…”

A method for isolating and culturing placental cells from failed early equine pregnancies

“…Early pregnancy loss (EPL) remains a significant cause of reproductive wastage in mammals [1][2][3][4][5] but the underlying aetiologies are often unknown [6,7]. A retrospective study in horses showed a speculative cause for EPL was found in just 16% of cases [8].…”

The high platelet counts as predictor for early foetal demise

“…The efficiency of human reproduction maximized at approximately 30% per cycle [ 23 ], yet a significant number of these pregnancies end with spontaneous miscarriage. Around one million of early pregnancy loss occur before 12 weeks’ gestation each year in the United States [ 17 , 24 ]. In addition, pregnancy loss before missed menses occurs in a significant proportion of women.…”

“…Early foetal demise occurs in 10% of all clinically recognized pregnancies and 80% of pregnancy losses occur in the first trimester [ 16 ]. Early foetal demise impacts around one million women in the United States each year [ 17 ]. Although genetic abnormalities are the most common cause of first trimester miscarriage, many other factors including the prothrombotic state may also contribute [ 14 ].…”