Increasing Survivors of Anthracycline-related Cardiomyopathy with Breast Cancer in Trastuzumab Era: Thirty-one-Year Trends in a Japanese Community
Mitsuhiro Watanabe,
Shinya Fujiki,
Yuji Okura
et al.
Abstract:BACKGROUND
Trastuzumab has improved breast cancer (BC) prognosis and reduced anthracycline use. However, the characteristic changes of anthracycline-related cardiomyopathy (ARCM) in patients with BC remain unclear. We sought to update our knowledge of ARCM in the trastuzumab era.
METHODS
This was a retrospective observational cohort study. A total of 2,959 patients with BC treated with anthracyclines in three regional cancer centers in Niigata City between 1990 and 2020 were included. Seventy-five patients (2.… Show more
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