Increasing stocking density causes inhibition of metabolic–antioxidant enzymes and elevates mRNA levels of heat shock protein 70 in rainbow trout

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“…Li et al (2006) found that increasing stocking density induced the expression of stress related protein HSP70 in rainbow trout. Aksakal, Ekinci, Erdogan, Beydemir, Alm, & Ceyhun (2011) found increasing stocking density elevated mRNA levels of HSP70 in rainbow trout. HSP70 mRNA level in liver of tilapia increased obviously after 48h acute crowding stress (Qiang, Yang, He, Wang, Xu, & Zhu, 2014).…”

“…SOD activity of GIFT strain tilapia was significantly affected by stocking density (Kpundeh, He, Qiang, Hong, & Xu, 2014). Aksakal et al (2011) found increasing stocking density caused inhibition of antioxidant enzymes. Liu (2006) found crowding stress increased the free radical level and inhibited antioxidant enzymes activity in Chinese sturgeon.…”

Simple methanesulfonates are hydrolyzed by the sulfatase carbonic anhydrase activity

“…However, it is critically important to explore further classes of potent CAIs in order to detect compounds with a different inhibition profiles as compared to the sulfonamides and their bioisosteres and to find novel applications for the inhibitors of these widespread enzymes, in particular tumor-related isoforms. Studies regarding interactions of different proteins and enzymes are of particular interest for toxicologists and medicinal chemists [41][42][43][44][45][46][47][48] and many such investigations exist in the literature [49][50][51][52][53][54][55] . The discovery of novel inhibitors of CAs has also gained great attention in the recent years.…”

Heavy metal ion inhibition studies of human, sheep and fish α-carbonic anhydrases

“…Most metal ions are toxic to humans, animals, plants and other living organisms. Because of bioaccumulation, man and other organisms are at great risk of health hazards associated with toxic metals [13][14][15][16][17][18][19][20][21][22] . Several studies shown that people in different regions of the world are being exposed to…”