Increasing Incidence of All Stages of Kidney Cancer in the Last 2 Decades in the United States: An Analysis of Surveillance, Epidemiology and End Results Program Data

Hock, Lynette M.; Lynch, James C.; Balaji, K.C.

doi:10.1016/s0022-5347(05)65382-7

Cited by 369 publications

(178 citation statements)

References 15 publications

Supporting

Mentioning

165

Contrasting

Unclassified

Order By: Relevance

“…Thus, the purpose of our study was to investigate the use of multiphase contrast-enhanced MR imaging in differentiating between the common benign and malignant histologic subtypes carcinoma (1)(2)(3)(4)(5). Because of increased use of imaging, about 70% of cases of renal cortical tumor are now detected incidentally; both the size and stage of tumors at presentation have been declining, and benign and indolent biologic subtypes represent about 45% of cases (6)(7)(8)(9)(10)(11)(12)(13)(14)(15). As a consequence, the management of renal cortical tumors has been undergoing a transformation, with increasing emphasis being placed on minimally invasive approaches that preserve renal tissue and function while achieving optimal oncologic control (14,15).…”

Section: Discussionmentioning

confidence: 99%

Renal Cortical Tumors: Use of Multiphasic Contrast-enhanced MR Imaging to Differentiate Benign and Malignant Histologic Subtypes

Vargas

Chaim²,

Lefkowitz³

et al. 2012

Radiology

View full text Add to dashboard Cite

Purpose:To investigate the use of quantitative multiphasic contrast material-enhanced magnetic resonance (MR) imaging in differentiating between common benign and malignant histologic subtypes of renal cortical tumors. Materials and Methods:The institutional review board waived informed consent and approved this retrospective HIPAA-compliant study of 138 patients who underwent preoperative contrastenhanced MR imaging during the period of January 2004-December 2008. At surgery, 152 renal tumors were identified (77 clear cell, 22 papillary, 18 chromophobe, and 10 unclassified carcinomas; 16 oncocytomas; nine angiomyolipomas). Three readers independently identified and measured the most-enhanced area in each tumor and placed corresponding regions of interest in similar positions on images from the precontrast, corticomedullary, nephrographic, and excretory phases. The percentage change in signal intensity (%SI change) between precontrast imaging and each postcontrast phase was calculated.Interreader agreement was evaluated by using the overall concordance correlation coefficient (OCC). A linear mixed-effects model was used to estimate and compare the trajectories of the means of log %SI change across all phases between the six histologic subtypes. results:Interreader agreement was substantial to almost perfect (OCC, 0.77-0.88). The %SI change differed significantly between clear cell carcinomas and papillary and chromophobe carcinomas in all phases of enhancement (P , .0001-.0120). In addition, %SI change was significantly higher in angiomyolipomas than in clear cell carcinomas, but only in the corticomedullary phase (P = .0231). Enhancement did not differ significantly between clear cell carcinoma and oncocytoma in any phase (P = .2081-.6000). conclusion:Quantitative multiphase contrast-enhanced MR imaging offers a widely available, reproducible method to characterize several histologic subtypes of renal cortical tumors, although it does not aid differentiation between clear cell carcinomas and oncocytomas.q RSNA, 20121 From the Departments of Radiology (H

show abstract

Section: Discussionmentioning

confidence: 99%

Renal Cortical Tumors: Use of Multiphasic Contrast-enhanced MR Imaging to Differentiate Benign and Malignant Histologic Subtypes

Vargas

Chaim²,

Lefkowitz³

et al. 2012

Radiology

View full text Add to dashboard Cite

show abstract

“…[1][2][3] Regionally advanced or metastatic cases account for approxi-consistency is the clear cell subtype. Variants such as granular cell, papillary, or sarcomatoid appear more consistently refractory to the immune approach.…”

Section: Introductionmentioning

confidence: 99%

Immunotherapy of Metastatic Renal Cell Cancer

Fishman

Seigne

2002

Cancer Control

View full text Add to dashboard Cite

“…Na taj način se, u odnosu na klasičnu nefrektomiju, smanjuje gubitak nefronske mase, ali uz zadržani onkološki učinak. jenata u kojih je tumor incidentalno pronađen kao posljedica uporabe suvremenih dijagnostič-kih sredstava 10 . U naših pacijenata je 1979. godine samo 6 % pacijenata bilo bez siptoma vezanih uz KB, dok ih je 2012. godine bilo čak 75 %.…”

Section: Raspravaunclassified

Incidence, clinical evaluation and surgical treatment of patients with renal cell cancer: 40-years of experience in the University Hospital Rijeka

et al. 2017

View full text Add to dashboard Cite

Sažetak. Cilj: Ispitati učestalost, kliničku evaluaciju i kirurško liječenje pacijenata s karcinomom bubrega (KB). Pacijenti i metode: Retrospektivnim istraživanjem bili su obuhvaćeni svi pacijenti u Kliničkom bolničkom centru Rijeka koji su između 1. siječnja 1972. i 31. prosinca 2012. godine operirani zbog KB-a. Rezultati: U promatranom razdoblju u našem centru zbog KB-a bilo je operirano 1045 pacijenata. Broj pacijenata se tijekom vremena povećao, s 5 pacijenata godišnje početkom 70-ih godina na preko 50 posljednjih nekoliko godina. Broj asimptomatskih pacijenata povećao se s 6 % na 75 %. Prosječna dob pacijenata bila je 63 godine (raspon 21 -86 godina). Nefrektomija je učinjena u 95,3 % pacijenata, u 2,6 % parcijalna nefrektomija, a u 2,1 % eksplorativna lumbotomija. U promatranom razdoblju 5-godišnje preživljenje bilo je u 64 %, a 10-godišnje preživljenje 47 %. Zaključak: Učestalost KB-a se tijekom posljednja četiri desetljeća višestruko povećala. Novije dijagnostičke metode omogućuju njegovo otkrivanje u ranijoj fazi, a samim time se omogućuje poštednije kirurško liječenje, ne umanjujući onkološki učinak.Ključne riječi: incidencija; karcinom bubrega; nefrektomija; parcijalna nefrektomija; preživljenje Abstract. Aim: To evaluate incidence, clinical evaluation and surgical treatment of our patients with renal cell cancer (RCC). Patients and methods: We retrospectively analyzed all patients with RCC operated in University Hospital Rijeka from January 1 st 1972 to December 31 st 2012. Results: In observed period 1045 patients were operated because of RCC. Number of operated patients has increased during time from 5 in the begining of 70-ties to more than 50 in the few last years. The number of asymptomatic patients has increased from 6% to 75%. The mean age was 63 years (range 21-86). Nephrectomy wasperformed in 95.3% patients, nephron sparing surgery in 2.6% and explorative lumbotomy in 2,1% of patients. The 5-year survival was 64% and 10-year survival 47%. Conclusion: The incidence of RCC substantialy increased during time. The new diagnostic methods found RCC in earlier phase and the nephron sparing surgery can be performed without negative influence on oncological outcome.

show abstract

Increasing Incidence of All Stages of Kidney Cancer in the Last 2 Decades in the United States: An Analysis of Surveillance, Epidemiology and End Results Program Data

Cited by 369 publications

References 15 publications

Renal Cortical Tumors: Use of Multiphasic Contrast-enhanced MR Imaging to Differentiate Benign and Malignant Histologic Subtypes

Renal Cortical Tumors: Use of Multiphasic Contrast-enhanced MR Imaging to Differentiate Benign and Malignant Histologic Subtypes

Immunotherapy of Metastatic Renal Cell Cancer

Incidence, clinical evaluation and surgical treatment of patients with renal cell cancer: 40-years of experience in the University Hospital Rijeka

Contact Info

Product

Resources

About