Increasing incidence and survival of head and neck cancers in Denmark: a nation-wide study from 1980 to 2014

Jakobsen, Kathrine Kronberg; Grønhøj, Christian; Jensen, David Hebbelstrup; Karnov, Kirstine; Agander, Tina Klitmøller; Specht, Lena

doi:10.1080/0284186x.2018.1438657

Cited by 55 publications

(69 citation statements)

References 28 publications

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“…An equal number of men and women participated, which does not reflect the actual distribution of HNC in the Danish population, where HNC more frequently affects men than women [3]. This could potentially have affected the representativeness of our study population.…”

Section: Strengths and Limitationsmentioning

confidence: 97%

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To eat is to practice—managing eating problems after head and neck cancer

et al. 2019

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Section: Strengths and Limitationsmentioning

confidence: 97%

“…Annually, approximately 900,000 people worldwide are diagnosed with HNC [2] making it a substantial contributor to morbidity and mortality. The incidence but also the survival has increased during recent years [3]. Hence, the population of HNC survivors is increasing and so is the requirement for appropriate rehabilitation services [4].…”

Section: Introductionmentioning

confidence: 99%

To eat is to practice—managing eating problems after head and neck cancer

et al. 2019

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“…The survival rates for head and neck cancer vary depending on the site involved (7). Previous European and American population-based studies reported that the 5-year relative survival of German people with OC diagnosed in 2002-2006 was 54.6% (8), whereas that of Danish people with head and neck cancer was 62.4% (2010-2014) (9). For American individuals with cancer in the oral cavity, oropharynx, and subsites (base of tongue, hard palate, tonsil, etc.…”

Section: ' Introductionmentioning

confidence: 99%

Survival trends of patients with oral and oropharyngeal cancer treated at a cancer center in São Paulo, Brazil

Kowalski¹,

Oliveira²,

López³

et al. 2020

Clinics

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OBJECTIVE:We aimed to estimate the overall survival (OS) and conditional survival (CS) in patients diagnosed with oral and oropharyngeal squamous cell carcinoma (SCC) and to determine their survival trends. METHODS:The study included all consecutive patients treated at the A.C. Camargo Cancer Center for oral or oropharyngeal SCC between 2001 and 2012. Data were obtained from the Hospital Cancer Registry. OS and CS were analyzed using the Kaplan-Meier method to evaluate the probability of survival with Cox predictor models. RESULTS: Data of 505 oral and 380 oropharyngeal SCC patients obtained in 2001-2006 and 2007-2012 were analyzed. Most of the oral SCC (59%) and oropharyngeal SCC (90%) patients had stages III-IV SCC. The 5-year OS for patients with oral SCC was 51.7%, with no significant difference between the first and second periods. The CS rates in 2007-2012 were 65% after the first year and 86% up to the fifth year. For oropharyngeal SCC, the 5-year OS rate was 45.0% in the first period. The survival rate increased to 49.1% from 2007 to 2012, with a reduction in the risk of death (HR=0.69;0.52-09.2). The CS estimates from 2007 to 2012 were 59% after the first year and 75% up to the fifth year. CONCLUSION: Survival across the two time periods remained stable for oral SCC but showed a significant increase for oropharyngeal SCC, possibly because of improvements in the patients' response to radiotherapy, such as intensity-modulated radiation therapy, and the use of more accurate diagnostic imaging approaches.

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“…The incidence of head and neck cancer (HNC) has increased to approximately 900.000 new cases worldwide in 2018 [1,2]. With a simultaneous increase in the relative survival [3], the population of patients treated for HNC is increasing.…”

Section: Introductionmentioning

confidence: 99%

Rationale and design of a randomised controlled trial investigating the effect of multidisciplinary nutritional rehabilitation for patients treated for head and neck cancer (the NUTRI-HAB trial)

Kristensen

Wessel²,

Beck

et al. 2020

Nutr J

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Background: Eating problems frequently affect quality of life and physical, psychological and social function in patients treated for head and neck cancer (HNC). Residential rehabilitation programmes may ameliorate these adverse effects but are not indicated for all individuals. Systematic assessment of rehabilitation needs may optimise the use of resources while ensuring referral to rehabilitation for those in need. Yet, evidence lacks on which nutrition screening and assessment tools to use. The trial objectives are: 1) To test the effect of a multidisciplinary residential nutritional rehabilitation programme compared to standard care on the primary outcome body weight and secondary outcomes health-related quality of life, physical function and symptoms of anxiety and depression in patients curatively treated for HNC and 2) To test for correlations between participants' development in outcome scores during their participation in the programme and their baseline scores in Nutritional Risk Screening 2002 (NRS 2002), the Scored Patient-Generated Subjective Global Assessment Short Form (PG-SGA SF), and M. D. Anderson Dysphagia Inventory (MDADI) and to assess sensitivity, specificity and predictive values of the three tools in relation to a clinically relevant improvement in outcome scores.

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Increasing incidence and survival of head and neck cancers in Denmark: a nation-wide study from 1980 to 2014

Abstract: This nation-wide study showed a significant rise in incidence of HNC for men and women along with a significant increase in relative survival. Oropharyngeal cancer had the highest increase in incidence followed by hypopharyngeal cancer which showed the poorest survival of HNCs.

Cited by 55 publications

References 28 publications

To eat is to practice—managing eating problems after head and neck cancer

To eat is to practice—managing eating problems after head and neck cancer

Survival trends of patients with oral and oropharyngeal cancer treated at a cancer center in São Paulo, Brazil

Rationale and design of a randomised controlled trial investigating the effect of multidisciplinary nutritional rehabilitation for patients treated for head and neck cancer (the NUTRI-HAB trial)

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