Increasing frequency and severity of odontogenic infection requiring hospital admission and surgical management

Fu, Benjamin; McGowan, Kelly; Sun, Jiandong; Batstone, Martin

doi:10.1016/j.bjoms.2020.01.011

Cited by 38 publications

(49 citation statements)

References 24 publications

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“…Consistent with previous reports, we observed a distinct and significant difference in the prevalence of mandibular molars versus all other teeth as the origin of the most severe infections [3,20,45]. In particular, the third and second lower molars were highly represented in our material.…”

Section: Discussionsupporting

confidence: 91%

“…However, OIs can sometimes spread to the surrounding tissues and further to the deeper structures of the neck. In terms of clinical research, it is interesting that severe OIs have become more frequent in recent decades [1][2][3][4][5]. Deep neck infections are often caused by odontogenic foci [2,6,7], which may, in the most severe cases, be fatal [8].…”

Section: Introductionmentioning

confidence: 99%

“…Tooth extractions and root canal treatments are the most common dental procedures preceding these severe infection complications, particularly if not performed lege artis [20]. Previously, it has been shown that most patients visit outpatient care for the same symptoms before being admitted to hospital [3,21,22]; thus, diagnosis and effective early treatment of the infection appear to be challenging.…”

Section: Introductionmentioning

confidence: 99%

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Health status in patients hospitalised for severe odontogenic infections

Furuholm

Rautaporras

Uittamo

et al. 2021

Acta Odontologica Scandinavica

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Objective: Previous findings refer to certain predisposing medical conditions that compound the risk of developing severe and potentially lethal acute odontogenic infections (OI). The objective of this study was to clarify this rationale and infection severity in general. Material and methods: Records of patients aged !18 years requiring hospital care for deep OI were retrospectively investigated. The main outcome variable was need for intensive care unit (ICU) treatment. Additional outcome variable was occurrence of infection complications and/or distant infections. Several parameters describing patients' prior health and recent dental treatment were set as independent variables. Results: Of the 303 acute OI patients included, 71 patients (23%) required treatment in the ICU, with no significant difference between previously healthy and patients with disease history. OIs originating from teeth in the mandible compared with maxilla had 7.8-fold risk (p ¼ .007) for ICU treatment in binary logistic regression analyses. Elevated levels of infection parameters at hospital admission predicted further ICU stay. Infection complications and/or distant infections occurred in 7.6% of patients, of which septicaemia and pneumonia were the most common. The mortality rate was 0.3%. Infection complications and/or distant infections occurred significantly more often in smokers (p ¼ .001) and in patients with excessive consumption of alcohol or drugs (p ¼ .025), however smoking showed 3.5folded independent risk for infection complications and/or distant infections (p ¼ .008) in logistic regression. Conclusions: Severe OIs often occur in previously healthy patients. Smokers in particular are prone to the most serious OIs.

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Health status in patients hospitalised for severe odontogenic infections

Furuholm

Rautaporras

Uittamo

et al. 2021

Acta Odontologica Scandinavica

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“…Consideration needs be given to developing virtual consultations to include video conferencing with patients where possible, as this aspect of healthcare becomes more widely utilised. Research has shown that trismus is the most common finding in CFI 14 , which is also reflected in our study (Table 3). Further analysis of our study shows that proportionally more patients presented with ≥3 symptoms of serious CFI during COVID-19 lockdown which reflected the later presentation of these patients.…”

Section: Discussionsupporting

confidence: 88%

Impacts of lockdown during the SARS-CoV-2 pandemic on patients presenting with cervicofacial infection of odontogenic origin: a comparative study

Dawoud

Kent

2021

British Journal of Oral and Maxillofacial Surgery

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Introduction The SARS-CoV-2 pandemic caused unprecedented disruption to primary and secondary healthcare services. Our aim was to explore whether the pandemic had any impact on patients presenting with cervicofacial infections (CFI) of odontogenic origin to the secondary care and their management. Methods Comparative analysis was carried out evaluating prospective and retrospective consecutively admitted patients with a diagnosis of CFI of odontogenic origin in the COVID-19 lockdown period from 15 th March to 15 th June 2020 and pre COVID-19 during the same period of the previous year. Data included patient demographics, co-morbidities, systemic inflammatory response syndrome (SIRS) status on admission, clinical features, prior treatment in primary care, source of referral, SARS-CoV-2 antigen status, treatment received in secondary care, intra-operative findings, and whether escalation of the level of care was required. Results Across both cohorts there were one hundred and twenty-five (125) patients admitted with CFI of odontogenic origin, with a 33% reduction ((n = 75 (2019) vs. n = 50 (2020)) in number of patients admitted during COVID-19 lockdown. There was no difference between the cohorts in terms of age (p = 0.192), gender (p = 0.609) or major co-morbidities (p = 0.654). Proportionally more patients in the COVID-19 group presented with SIRS (p = 0.004). This group of patients persisted with symptoms for longer before presenting to secondary care (p = 0.003), more delay from hospital admission to surgical intervention (p < 0.005) and had longer length of hospital stay (p = 0.001). More patients required extra-oral surgical drainage during COVID-19 (p = 0.056). Conclusions This study suggests that the COVID-19 lockdown has had adverse effects on the presentation of CFI of odontogenic origin and its management within a Regional Acute Maxillofacial Service. Commissioners and clinicians should endeavour to plan for adequate primary and secondary care provision during any future local lockdowns to ensure that patient care is optimised.

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“…Саме тому, захворювання, розвиток яких асоційований з утворенням плівок на поверхнях твердих та м'яких тканин організму, важко піддаються лікуванню і створюють суттєву загрозу життю пацієнтів [7,8,9,10].…”

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Relationship Between Adhesive and Film-Forming Properties of Staphylococcus Spp. - Pathogens of Infectious Inflammatory Diseases in Soft Tissues of Jaw and Facial Area

Faustova

2021

Act. Probl. of the Modern Med.

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The aim of the study was to establish the relationship between film-forming and adhesive properties of clinical isolates of Staphylococcus spp. Materials and methods. The study included 20 clinical isolates of S. aureus and 10 isolates of S. epidermidis obtained from purulent exudates in patients with infectious inflammatory diseases of soft maxillofacial tissues. Cultivation of these isolates was performed according to standard methods. The assessment of the adhesive properties of the clinical isolates of microorganisms under the study was performed using the standard method of V. I. Brillis et al. Adhesive properties were evaluated by the index of microorganism adhesion. The study of the film-forming property of clinical isolates was performed using the spectrophotometric method of MtP-test "microtiter plate test" by G.D. Christensen. The correlation coefficient (r-Pearson) was applied to determine the relationship between the variables. Results. Clinical strains of S. aureus have been found to possess high adhesive and film-forming properties. In turn, index of adhesion of clinical isolates of S. epidermidis indicates the moderate adhesive properties of the pathogen. Moreover, S. epidermidis showed a moderate ability to form biofilms. The study had shown a close relationship between the adhesion and film formation in clinical isolates of the genus Staphylococcus. Conclusions. Clinical isolates of S. aureus have been found to have high adhesive and film-forming properties. Isolates of S. epidermidis show a moderate ability to adhere and form biofilms. There is a direct strong correlation between the adhesive and film-forming properties of microorganisms of the genus Staphylococcus.

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Increasing frequency and severity of odontogenic infection requiring hospital admission and surgical management

Cited by 38 publications

References 24 publications

Health status in patients hospitalised for severe odontogenic infections

Health status in patients hospitalised for severe odontogenic infections

Impacts of lockdown during the SARS-CoV-2 pandemic on patients presenting with cervicofacial infection of odontogenic origin: a comparative study

Relationship Between Adhesive and Film-Forming Properties of Staphylococcus Spp. - Pathogens of Infectious Inflammatory Diseases in Soft Tissues of Jaw and Facial Area

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