Increasing Adherence with Topical Agents for Atopic Dermatitis

Patel, Niketa A.; D’Ambra, Veronica; Feldman, Steven R.

doi:10.1007/s40257-017-0261-5

Cited by 50 publications

(40 citation statements)

References 51 publications

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“…The differences were, however, not significant . Adherence to topical agents in patients with atopic dermatitis ranged between 32% and 100%, in psoriasis patients between 27 and 75% . Adherence to oral prednisolone therapy in patients with moderate to severe hand dermatitis was 85% .…”

Section: Factors Influencing Treatment Adherencementioning

confidence: 99%

“…The administration route (topical, oral, subcutaneous, intravenous) is a very important treatment‐related factor and has been analysed in many studies …”

Section: Factors Influencing Treatment Adherencementioning

confidence: 99%

“…The administration route (topical, oral, subcutaneous, intravenous) is a very important treatment-related factor and has been analysed in many studies. 34,[51][52][53][54][55] Topical therapies are the cornerstone of treatment in dermatology. One of their benefits is that they bring the pharmacological agent precisely to the affected area, whilst limiting systemic effects.…”

Section: Treatment-relatedmentioning

confidence: 99%

See 2 more Smart Citations

A systematic review of factors influencing treatment adherence in chronic inflammatory skin disease – strategies for optimizing treatment outcome

Eicher

Knop

Aszodi

et al. 2019

Acad Dermatol Venereol

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Adherence describes how a patient follows a medical regime recommended by a healthcare provider. Poor treatment adherence represents a complex and challenging problem of international healthcare systems, as it has a substantial impact on clinical outcomes and patient safety and constitutes an important financial burden. Since it is one of the most common causes of treatment failure, it is extremely important for physicians to reliably distinguish between non‐adherence and non‐response. This systematic review aims to summarize the current literature on treatment adherence in dermatology, focusing on chronic inflammatory skin diseases such as psoriasis, atopic dermatitis and acne. A systematic literature search was performed using the PubMed Database, including articles from 2008 to 2018. Low treatment adherence is a multidimensional phenomenon defined by the interplay of numerous factors and should under no circumstances be considered as the patient's fault alone. Factors influencing treatment adherence in dermatology include patient characteristics and beliefs, treatment efficacy and duration, administration routes, disease chronicity and the disease itself. Moreover, the quality of the physician‐patient relationship including physician‐time available for the patient plays an important role. Understanding patients’ adherence patterns and the main drivers of non‐adherence creates opportunities to improve adherence in the future. Strategies to increase treatment adherence range from reminder programs to simplifying prescriptions or educational interventions. Absolute adherence to treatment may not be realistically achievable, but efforts need to be made to raise awareness in order to maximize adherence as far as possible.

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Section: Factors Influencing Treatment Adherencementioning

confidence: 99%

“…The administration route (topical, oral, subcutaneous, intravenous) is a very important treatment‐related factor and has been analysed in many studies …”

Section: Factors Influencing Treatment Adherencementioning

confidence: 99%

Section: Treatment-relatedmentioning

confidence: 99%

See 1 more Smart Citation

A systematic review of factors influencing treatment adherence in chronic inflammatory skin disease – strategies for optimizing treatment outcome

Eicher

Knop

Aszodi

et al. 2019

Acad Dermatol Venereol

View full text Add to dashboard Cite

show abstract

“…Adherence to treatment in AD is complex and multifaceted. Reasons for suboptimal adherence include complex instructions, lack of trust in the physician, displeasure with the topical agent vehicle, time burden of applying a topical agent, corticosteroid phobia, and cost of the medication . Simple measures may promote adherence and improve treatment outcomes.…”

Section: Introductionmentioning

confidence: 99%

Rapid, successful treatment of atopic dermatitis recalcitrant to topical corticosteroids

Lewis

Feldman

2018

Pediatric Dermatology

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Atopic dermatitis is responsive to midpotency topical corticosteroids, which are the mainstay of treatment, yet many patients have disease that is "resistant" to triamcinolone prescribed for outpatient use. Such resistance is often due to poor adherence, but patients and caregivers may remain adamant that the steroid was ineffective and assure the physician that it was applied as recommended. We describe the case of a young girl with a 2-year history of atopic dermatitis resistant to triamcinolone whose condition rapidly improved with continued use of triamcinolone. Our case raises the ethical dilemma of whether physicians should base treatment plans on what patients report or what evidence on adherence suggests.

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“…Nonetheless it is important to realize that investing time in eczema care is not only intended to improve outcomes but also to prevent unnecessary disease burden and in some cases even to prevent harm. I would therefore encourage all those treating people with eczema to read this review and invest in educating their patients with eczema, whichever way, as that certainly causes no harm and might even prevent it.…”

mentioning

confidence: 99%