Increases in Acute Hepatitis C Virus Infection Related to a Growing Opioid Epidemic and Associated Injection Drug Use, United States, 2004 to 2014

Zibbell, Jon E.; Asher, Alice; Patel, Ravi R; Kupronis, Ben; Iqbal, Kashif; Ward, John W.; Holtzman, Deborah

doi:10.2105/ajph.2017.304132

Cited by 565 publications

(389 citation statements)

References 16 publications

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“…Since these recommendations were established in 2012, HCV epidemiology in the United States has changed. Hepatitis C infection incidence nearly quadrupled from 2010 to 2017, primarily driven by increased injection drug use related to the opioid epidemic . CDC viral hepatitis surveillance data indicate progressively increasing acute HCV infection incidence each year from 2009 through 2017.…”

Section: Universal and Risk‐based Hepatitis C Screening And Follow‐upmentioning

confidence: 99%

Hepatitis C Guidance 2019 Update: American Association for the Study of Liver Diseases–Infectious Diseases Society of America Recommendations for Testing, Managing, and Treating Hepatitis C Virus Infection

2020

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Section: Universal and Risk‐based Hepatitis C Screening And Follow‐upmentioning

confidence: 99%

Hepatitis C Guidance 2019 Update: American Association for the Study of Liver Diseases–Infectious Diseases Society of America Recommendations for Testing, Managing, and Treating Hepatitis C Virus Infection

2020

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“…The number of deaths in Baltimore has been sharply driven by illicitly manufactured fentanyl, which has tripled overdose deaths from 2015 to 2016 (CDC, 2018; MDH, 2017). Other consequences of the opioid epidemic include increases in injection drug use (IDU), heightened transmission risk of hepatitis C and HIV, and an economic burden of $78.5 billion annually (Zibbel et al, 2018; CDC, 2018; Florence, Luo, Xu, & Zhou, 2016). …”

Section: Introductionmentioning

confidence: 99%

Challenges on the road to recovery: Exploring attitudes and experiences of clients in a community-based buprenorphine program in Baltimore City

Truong

Krawczyk

Dejman

et al. 2019

Addictive Behaviors

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Objective: This qualitative study identifies and describes experiences and challenges to retention of individuals with opioid use disorder (OUD) who participated in a low-threshold combined buprenorphine-peer support treatment program in Baltimore. Methods: In-depth semi-structured interviews with staff and former clients of the Project Connections Buprenorphine Program (PCBP) (9 people) and focus group discussions with current and previous clients of PCBP (7 people) were conducted. Content analysis was used to extract themes regarding barriers to enrolling and remaining in, and transitioning from the program. Results: Primary challenges identified by the participants included struggles with cravings and symptoms of withdrawal, comorbid mental health issues, criminal justice system involvement, medication stigma, and conflicts over level of flexibility regarding program requirements and the role of employment. Conclusions: This study identified several obstacles clients face when seeking care through a combined bupre- norphine-peer support model. Findings highlight potential programmatic factors that can be improved and additional resources that may support treatment retention rates and better outcomes. Despite challenges, low- threshold and community-based programs can increase access to effective maintenance treatment for OUD, especially among vulnerable populations who may not have access to formal health services.

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“…The need for better and expanded access to treatment for opioid use disorders has become increasingly evident as the consequences of the opioid epidemic in the United States have grown (Campbell et al 2017; Dowell et al 2017; Rudd et al 2016; Zibbell et al 2018). Development of better treatments would be aided by a better understanding of the multiple complex influences on drug use to identify additional therapeutic targets and, perhaps, guide the timing of delivery of existing treatments.…”

Section: Introductionmentioning

confidence: 99%

Before and after: craving, mood, and background stress in the hours surrounding drug use and stressful events in patients with opioid-use disorder

et al. 2018

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Stress increased before stressful-event entries, but was less evident before drug use. Craving increased in the hours before drug use and stressful events-and remained elevated in the hours after either event. These results suggest a stronger link between drug use and craving than between drug use and stress. Lapses to drug use did not improve mood or reduce stress, at least not at our 1-h-bin time resolution, suggesting that if such benefits exist, they are brief.

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Increases in Acute Hepatitis C Virus Infection Related to a Growing Opioid Epidemic and Associated Injection Drug Use, United States, 2004 to 2014

Abstract: These findings strongly suggest that the national increase in acute HCV infection is related to the country's opioid epidemic and associated increases in IDU.

Cited by 565 publications

References 16 publications

Hepatitis C Guidance 2019 Update: American Association for the Study of Liver Diseases–Infectious Diseases Society of America Recommendations for Testing, Managing, and Treating Hepatitis C Virus Infection

Hepatitis C Guidance 2019 Update: American Association for the Study of Liver Diseases–Infectious Diseases Society of America Recommendations for Testing, Managing, and Treating Hepatitis C Virus Infection

Challenges on the road to recovery: Exploring attitudes and experiences of clients in a community-based buprenorphine program in Baltimore City

Before and after: craving, mood, and background stress in the hours surrounding drug use and stressful events in patients with opioid-use disorder

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