Increased urinary volumes in symptomatic Ménière’s Disease

Abstract

Objective. The purpose of the research is to test the measurement of the total urinary volume, induced by the diuretic osmotic action of mannitol, in a group of symptomatic MD patients and in healthy controls. Results. An altered excretory urinary volume after mannitol challenge was observed in symptomatic MD (874.3 ± 302.1) compared to healthy volunteers (361.7 ± 181.6). (p = 0.0001) This easy and self-administered method might be proposed to replace the analysis of the urinary sugars' concentration in symptomatic MD patients.