Increased tibiofemoral cartilage contact deformation in patients with anterior cruciate ligament deficiency

Velde, Samuel K. Van de; Bingham, Jeffrey T.; Hosseini, Ali; Kozánek, Michal; DeFrate, Louis E.; Gill, Thomas J.; Li, Guoan

doi:10.1002/art.24965

Cited by 129 publications

(168 citation statements)

References 48 publications

(83 reference statements)

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“…Experimental studies by Bingham et al [58], Li et al [59], and Van de Velde et al [60] using biplane X-ray images of subjects in a full-extension weight-bearing position have showed that the contact centroids lie anterior to the anterior-posterior (AP) midline of the cartilage for both the lateral and medial compartments. Contact centroid estimation by the DSX-based model in the current study was consistent with those previous findings.…”

Section: Discussionmentioning

confidence: 99%

Subject-Specific Finite Element Modeling of the Tibiofemoral Joint Based on CT, Magnetic Resonance Imaging and Dynamic Stereo-Radiography Data in Vivo

Carey

Zheng

Aiyangar

et al. 2014

Journal of Biomechanical Engineering

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In this paper, we present a new methodology for subject-specific finite element modeling of the tibiofemoral joint based on in vivo computed tomography (CT), magnetic resonance imaging (MRI), and dynamic stereo-radiography (DSX) data. We implemented and compared two techniques to incorporate in vivo skeletal kinematics as boundary conditions: one used MRI-measured tibiofemoral kinematics in a nonweight-bearing supine position and allowed five degrees of freedom (excluding flexion-extension) at the joint in response to an axially applied force; the other used DSX-measured tibiofemoral kinematics in a weight-bearing standing position and permitted only axial translation in response to the same force. Verification and comparison of the model predictions employed data from a meniscus transplantation study subject with a meniscectomized and an intact knee. The model-predicted cartilage-cartilage contact areas were examined against "benchmarks" from a novel in situ contact area analysis (ISCAA) in which the intersection volume between nondeformed femoral and tibial cartilage was characterized to determine the contact. The results showed that the DSX-based model predicted contact areas in close alignment with the benchmarks, and outperformed the MRI-based model: the contact centroid predicted by the former was on average 85% closer to the benchmark location. The DSX-based FE model predictions also indicated that the (lateral) meniscectomy increased the contact area in the lateral compartment and increased the maximum contact pressure and maximum compressive stress in both compartments. We discuss the importance of accurate, task-specific skeletal kinematics in subject-specific FE modeling, along with the effects of simplifying assumptions and limitations.

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Section: Discussionmentioning

confidence: 99%

Subject-Specific Finite Element Modeling of the Tibiofemoral Joint Based on CT, Magnetic Resonance Imaging and Dynamic Stereo-Radiography Data in Vivo

Carey

Zheng

Aiyangar

et al. 2014

Journal of Biomechanical Engineering

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“…One in vivo study has shown that the ratio of the medial to lateral contact area was 1.35 at 30 of flexion under nonweight-bearing conditions in healthy subjects (5). Van de Velde et al (20) estimated the in vivo tibiofemoral contact area based on matching dual fluoroscopy images to MR images during a single-leg quasistatic lunge. They reported that healthy subjects have a medial to lateral tibiofemoral contact area ratio of %1.55 between 0 and 15 of knee flexion.…”

Section: Discussionmentioning

confidence: 99%

“…Thus, the contact areas were measured directly in this study, instead of estimating the cartilage interference (19,20) based on the MR image acquired from different positions. Recent studies using segmented MR images have shown that MRI assessment of cartilage contact area is a valid method (12) and comparable to the pressure-sensitive film technique (13,14).…”

Section: Discussionmentioning

confidence: 99%

“…The majority of in vivo cartilage contact area measurements have evaluated the patellofemoral joint (13)(14)(15)(16)(17) of healthy subjects, subjects with anterior cruciate ligament deficiency, or patients with patellar subluxation (18)(19)(20). With regard to methodology used, cartilage-to-cartilage contact area analyses have been mainly conducted for MR images using 3D spoiled gradient-recalled (3D-SPGR) sequences (14)(15)(16).…”

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confidence: 99%

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In vivo tibiofemoral cartilage‐to‐cartilage contact area of females with medial osteoarthritis under acute loading using MRI

Shin

Souza

Kumar

et al. 2011

Magnetic Resonance Imaging

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Purpose: To investigate the effect of acute loading on in vivo tibiofemoral contact area changes in both compartments, and to determine whether in vivo tibiofemoral contact area differs between subjects with medial knee osteoarthritis (OA) and healthy controls. Materials and Methods:Ten subjects with medial knee OA (KL3) and 11 control subjects (KL0) were tested. Coronal three-dimensional spoiled gradient-recalled (3D-SPGR) and T 2 -weighted fast spin-echo FSE magnetic resonance imaging (MRI) of the knee were acquired under both unloaded and loaded conditions. Tibiofemoral cartilage contact areas were measured using image-based 3D models.Results: Tibiofemoral contact areas in both compartments significantly increased under loading (P < 0.001) and the increased contact area in the medial compartment was significantly larger than in the lateral compartment (P < 0.05). Medial compartment contact area was significantly larger in KL3 subjects than KL0 subjects, both at unloaded and loaded conditions (P < 0.05). Contact areas measured from 3D-SPGR and T 2 -weighted FSE images were strongly correlated (r ¼ 0.904). Conclusion:Females with medial OA increased tibiofemoral contact area in the medial compartment compared to healthy subjects under both unloaded and loaded conditions. The contact area data presented in this study may provide a quantitative reference for further cartilage contact biomechanics such as contact stress analysis and cartilage biomechanical function difference between osteoarthritic and healthy knees.

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“…[8][9][10][11][12][13][14][15] Combination of MR imaging and double fluoroscopy on knees during motion and various flexion angles show similar results (in healthy subject [16][17][18][19] and in subjects with torn cruciate ligaments [19][20][21] ). On the contrary, gaps among the joint surfaces are a common observation in knee arthroscopic operations.…”

Section: -3mentioning

confidence: 69%

The Tibiofemoral Joint Gaps - An Arthroscopic Study

2017

SDRP-JBE

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Abstract:The articular surfaces of the tibiofemoral jointcommonly appear to have gaps in between during Arthroscopy operations. However, the same joint surfaces appear to be in contact inMR images. This discrepancy may be attributed to the pressure of the saline injected into the joint duringarthroscopy operations, insertion of cannulas, or anesthesia and the resulting absence of compressive force on the joint. This study examines the effect of these factors. Seven candidates of knee arthroscopysurgery participated in the study. The tibiofemoral joint space was observed with the arthroscope in different knee and hip flexion angles, with and without saline pressure, and with and without external compressive load. In the totally extended knee position, the joint was closed on both the lateral and medial sides. In the flexed knee positions, some of the joints showed a gap in either medial or lateral sides or both. Removing saline pressure and applying external compressive force on the knees did not affect the gaps. As this phenomenon cannot be explained with the conventional joint biomechanics, there is a need to revise the biomechanics of the knee joint, probably with the aid of the concepts laid in the theory of biotensegrity.

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Increased tibiofemoral cartilage contact deformation in patients with anterior cruciate ligament deficiency

Cited by 129 publications

References 48 publications

Subject-Specific Finite Element Modeling of the Tibiofemoral Joint Based on CT, Magnetic Resonance Imaging and Dynamic Stereo-Radiography Data in Vivo

Subject-Specific Finite Element Modeling of the Tibiofemoral Joint Based on CT, Magnetic Resonance Imaging and Dynamic Stereo-Radiography Data in Vivo

In vivo tibiofemoral cartilage‐to‐cartilage contact area of females with medial osteoarthritis under acute loading using MRI

The Tibiofemoral Joint Gaps - An Arthroscopic Study

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