Increased Short-Term and Mid-Term Major Complications Were Observed in Elderly Patients with Renal Dysfunction after Surgical Ventricular Restoration

Xu, Fei; Song, Yangwu; Feng, Wei; Li, Xuan; Du, Junbao

doi:10.1532/hsf.1911

Cited by 1 publication

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“…A meta-analysis published in 2013 and including 49 studies, mostly in vascular and cardiac surgery, reported that eGFR less than 60 ml/min/1.73 m 2 was associated with a threefold increase in 30-day mortality risk for surgical patients 10 . A retrospective single-center study reported increased risks of postoperative all-cause mortality and major adverse events in elderly patients with preoperative renal dysfunction (defined as eGFR <60 ml/min/1.73 m 2 ) 17 .…”

Section: Discussionmentioning

confidence: 99%

Preoperative renal insufficiency predicts postoperative adverse outcomes in a mixed surgical population: a retrospective matched cohort study using the NSQIP database

Liao¹,

Chang

Chen

et al. 2023

International Journal of Surgery

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Background: The incidence of chronic kidney disease is increasing, but most cases are not diagnosed until the accidental finding of abnormal laboratory data or the presentation of severe symptoms. Patients with chronic kidney disease are reported to have an increased risk of postoperative mortality and morbidities, but previous studies mainly targeted populations undergoing cardiovascular surgery. The authors aimed to evaluate the risk of postoperative mortality and complications in a surgical population with preoperative renal insufficiency (RI). Materials and Methods: This retrospective cohort study used data from the National Surgical Quality Improvement Program database between 2013 and 2018 to evaluate the risk of postoperative morbidity and mortality in the surgical population. Patients with estimated glomerular filtration rate less than 60 ml/min/1.73 m2 were defined as the RI group. Propensity score matching methods and multivariate logistic regression were used to calculate the risk of postoperative morbidity and mortality. Results: After propensity score matching, 502 281 patients were included in the RI and non-RI groups. The RI group had a higher risk of 30-day in-hospital mortality (odds ratio: 1.54, 95% CI: 1.49–1.58) than the non-RI group. The RI group was associated with a higher risk of postoperative complications, including myocardial infarction, stroke, pneumonia, septic shock, and postoperative bleeding. The RI group was also associated with an increased risk of prolonged ventilator use for over 48 h, readmission, and reoperation. Conclusion: Patients with preoperative RI have an increased risk of postoperative 30-day mortality and complications. RI group patients with current dialysis, estimated glomerular filtration rate less than or equal to 30 ml/min/1.73 m2 or concomitant anemia had an elevated risk of postoperative mortality.

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Section: Discussionmentioning

confidence: 99%

Preoperative renal insufficiency predicts postoperative adverse outcomes in a mixed surgical population: a retrospective matched cohort study using the NSQIP database

Liao¹,

Chang

Chen

et al. 2023

International Journal of Surgery

View full text Add to dashboard Cite

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Increased Short-Term and Mid-Term Major Complications Were Observed in Elderly Patients with Renal Dysfunction after Surgical Ventricular Restoration

Abstract: Compared to patients with normal renal function, elderly SVR patients with renal failure have a higher incidence of short-term mechanical support, mid-term mortality, and MACCE events.

Cited by 1 publication

References 23 publications

Preoperative renal insufficiency predicts postoperative adverse outcomes in a mixed surgical population: a retrospective matched cohort study using the NSQIP database

Preoperative renal insufficiency predicts postoperative adverse outcomes in a mixed surgical population: a retrospective matched cohort study using the NSQIP database

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