Increased Risk of Preeclampsia with Assisted Reproductive Technologies

Kornfield, Molly S.; Gurley, Susan B.; Vrooman, Lisa A.

doi:10.1007/s11906-023-01250-8

Cited by 1 publication

(1 citation statement)

References 75 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 42 The absence of corpus luteum in HRC may result in a lack of important substances produced by the corpus luteum other than estradiol and progesterone, which may trigger PAS. 43 Estradiol and progesterone have been reported to be associated with extravillous trophoblast invasion. Therefore, there is a possibility that abnormal invasion may occur as a result of exogenous administration of these hormones.…”

Section: Discussionmentioning

confidence: 99%

Risk factors for non‐previa placenta accreta spectrum in pregnancies conceived through frozen embryo transfer during a hormone replacement cycle in Japan

Matsuo,

Kotani,

Tano

et al. 2024

Reprod Medicine & Biology

View full text Add to dashboard Cite

PurposeNon‐previa placenta accreta spectrum (PAS) is associated with assisted reproductive technology (ART), particularly frozen embryo transfer during hormone replacement therapy (HRC‐FET). We especially aimed to evaluate the prevalence and risk factors for non‐previa PAS in HRC‐FET pregnancies.MethodsOverall, 279 women who conceived through ART at three ART facilities and delivered at a single center were included in this retrospective study. Data regarding endometrial thickness at embryo transfer, previous histories, and type of embryo transfer—HRC‐FET, frozen embryo transfer during a natural ovulatory cycle (NC‐FET), and fresh embryo transfer (Fresh‐ET)—were collected. Univariable logistic regression analyses were conducted.ResultsThe prevalence of non‐previa PAS was 27/192 (14.1%) in the HRC‐FET group and 0 (0.0%) in both the NC‐FET and Fresh‐ET groups. Significantly high odds ratio [95% confidence interval] of non‐previa PAS was associated with a history of artificial abortion (6.45 [1.98–21.02]), endometrial thickness <8.0 mm (6.11 [1.06–35.12]), resolved low‐lying placenta (5.73 [2.13–15.41]), multiparity (2.90 [1.26–6.69]), polycystic ovarian syndrome (2.62 [1.02–6.71]), and subchorionic hematoma (2.49 [1.03–6.04]).ConclusionsA history of artificial abortion, endometrial thickness <8.0 mm, and resolved low‐lying placenta may help in antenatal detection of a high‐risk population of non‐previa PAS in HRC‐FET pregnancies.

show abstract

Section: Discussionmentioning

confidence: 99%