Increased Pulse Wave Velocity and Arterial Hypertension in Young Patients With Thoracic Aortic Endografts

Tzilalis, Vasilios D.; Kamvysis, D.; Panagou, Panagiotis; Kaskarelis, Ioannis; Lazarides, Miltos K.; Perdikides, Theodossios; Prassopoulos, Panagiotis; Boudoulas, Harisios

doi:10.1016/j.avsg.2011.06.021

Cited by 52 publications

(34 citation statements)

References 16 publications

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“…In the near future, the clinical investigator will introduce aortic function in daily clinical practice and it will be used as the measurement of LV function is used today. The clinical investigator will define the effect of intra-aortic devices, especially in young patients, on PWV [106] .…”

Section: Aortic Function: Concluding Remarksmentioning

confidence: 99%

Aortic Function: From the Research Laboratory to the Clinic

Boudoulas¹,

Vlachopoulos²,

Raman³

et al. 2012

Cardiology

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For many years, much of the pioneering research on aortic function was carried out by a small group of investigators frequently working away from the clinical environment in the research laboratory. The evaluation of aortic function using aortic pulse wave velocity, aortic distensibility, or other practical indices had yet to reach clinical threshold. It was necessary for the clinicians to take over and to apply these indices to the clinic. In this Odyssey, the work by the basic scientist was important to define the fundamental mechanisms of aortic function; however, it was the vision of the clinical investigator who recognized the importance of aortic function and introduced it into clinical practice. In the near future, the clinical investigator will introduce aortic function in daily clinical practice as the measurement of left ventricular function is used today. A close collaboration between the clinical and the basic investigator will be necessary in order to define the molecular mechanisms related to aortic wall synthesis and degradation of collagen and elastin. Application of these findings by the clinical investigator may help to delay or prevent aortic dysfunction related to aging or other conditions and diseases.

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Section: Aortic Function: Concluding Remarksmentioning

confidence: 99%

Aortic Function: From the Research Laboratory to the Clinic

Boudoulas¹,

Vlachopoulos²,

Raman³

et al. 2012

Cardiology

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“…4 As Lantelme et al 5 reported, stent-grafts seem to be associated with more wave reflections and increased ''augmented pressure'' after EVAR.…”

Section: Eplymentioning

confidence: 98%

Interpretation of the Relationship Between Changes in Pulse Wave Velocity and Vascular Interventions: A Word of Caution

Georgakarakos

Georgiadis

Kontopodis

et al. 2013

Journal of Endovascular Therapy

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I read with great interest the manuscript by Dr. Kadoglou and colleagues 1 regarding the changes in the aortic pulse wave velocity of patients undergoing endovascular repair of abdominal aortic aneurysms. As the authors aptly point out, this finding requires further evaluation with outcome data. I would like to know if there was a difference in the pulse pressure before and after surgery. The measurement of pulse pressure is easily obtainable, and there are outcome data based upon this measurement. Furthermore, it would be interesting if there is a difference in pulse pressure between open and endovascular repair and between thoracic and infrarenal aortic segments that underwent treatment.Again, I thank the authors for a most interesting publication on the alteration of flow dynamics after intervention.

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“…Proximal to TEVAR both the patient and the HV presented a clockwise IRF of around 35 cm 2 /s. However, inside and shortly distally of the TEVAR the patient presented a marked and sustained counterclockwise direction (IRF ¼ -30 cm 2 /s) while the HV presented clockwise rotation (IRF ¼ 20 cm 2…”

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confidence: 99%

“…The interaction between endograft and the dynamic anatomy of the thoracic aorta is not well characterized for repetitive physiologic stressors and subsequent issues related to long-term durability. TEVAR could also modify the flow and in the long term increase the risk of cardiovascular diseases (2). The alteration of flow characteristics in the heart and aorta have been related to atherosclerosis, aneurysms, and hypertension (3).…”

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confidence: 99%

Hemodynamics Changes in Aortic Flux Due to TEVAR Quantified by 4D-flow-MRI

Reyes

Guala

Palomares

et al. 2019

European Journal of Vascular and Endovascular Surgery

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Introduction: A benefit of carotid endarterectomy (CEA) within two weeks after carotid-related ischemic events was shown in multiple reports and guidelines *. However, a concrete timing and patient selection depending on neurologic impairment are debatable at present. Real risks of surgery and its influence on neurologic recovery in cases of Rankin 3 and more are debated. The aim of this study is an evaluation of our experience in early CEAs after the stroke. Methods: The cooperative experience of our clinics consists in 311 early CEA (male patients 65.9%, age 65.2AE7.5 years) within 14 days after acute ischemic event in 2010-2018. 22 (7.1%) patients underwent the systemic thrombolysis immediately after the admission. The main including criteria for surgery were stenoses of carotid bifurcation more than 60%, the neurological impairment up to 15 (NIHSS) or not exceeding Rankin 4, no signs of hemorrhage on CT and/or MR, and less than one third of hemisphere focus volume. The postoperative follow-up was evaluated on discharge, after 6 and 12 months. Results: The eversion CEA was performed in majority of cases (88.4%). The selective carotid shunt was applied in 7.7%, only in cases of critical clamping intolerance detected by NIRS .The serious adverse events immediate after the surgery were happened in 27 (8.7%) cases, including four postoperative strokes (1.2%), twelve hemorrhagic transformations (3.8%) and seven myocardial infarctions (2.3%). The common postoperative lethality amounted 2.9%. The neurologic improvement was detected in 75.8% within 10 days after the surgery, 87.5% within 6 months, and 89.7% within one year. No significant differences between patients with Rankin 0-2 and Rankin 3-4 were revealed in point of postoperative stroke (p¼0.072) and lethality (p¼0.054) amount or rehabilitation and recovery potency (p¼0.107). Conclusion: We conceive, the CEA within first two weeks after carotid-related ischemic events is enough safe, effective and indicated as soon as possible for treatment of well selected patients, among other for patients with severe neurologic impairment. References

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Increased Pulse Wave Velocity and Arterial Hypertension in Young Patients With Thoracic Aortic Endografts

Cited by 52 publications

References 16 publications

Aortic Function: From the Research Laboratory to the Clinic

Aortic Function: From the Research Laboratory to the Clinic

Interpretation of the Relationship Between Changes in Pulse Wave Velocity and Vascular Interventions: A Word of Caution

Hemodynamics Changes in Aortic Flux Due to TEVAR Quantified by 4D-flow-MRI

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