Increased Prevalence of Obstructive Sleep Apnea in Patients With Cleft Palate

Abstract

An increased prevalence of SDB and/or OSA exists in the population with cleft palate, with an even greater prevalence in patients with Pierre Robin syndrome. Definitive diagnosis of OSA by PSG is underused. We suggest that surgical management of SDB and/or OSA be followed by PSG to demonstrate resolution or persistence of symptoms to ensure appropriate further management.

Sleep Outcomes in Children with Single-Suture Craniosynostosis Compared with Unaffected Controls

“…Our study found a higher presence of parent-reported snoring among children aged 7 to 11 years with SSC compared with controls. Though preliminary, our results suggest that children with isolated SSC may have a higher risk for SDB, which is consistent with previous studies of other craniofacial anomalies (Cloonan et al, 2009;MacLean et al, 2009;Al-Saleh et al, 2011;Robison and Otteson, 2011;Plomp et al, 2012). To our knowledge, our study was the first to compare the occurrence of SDB between children with and without isolated SSC.…”

Sleep Outcomes in Children with Single-Suture Craniosynostosis Compared with Unaffected Controls

“…Our study found a higher presence of parent-reported snoring among children aged 7 to 11 years with SSC compared with controls. Though preliminary, our results suggest that children with isolated SSC may have a higher risk for SDB, which is consistent with previous studies of other craniofacial anomalies (Cloonan et al, 2009;MacLean et al, 2009;Al-Saleh et al, 2011;Robison and Otteson, 2011;Plomp et al, 2012). To our knowledge, our study was the first to compare the occurrence of SDB between children with and without isolated SSC.…”

Symptoms of Obstructive Sleep Apnea, Nasal Obstruction, and Enuresis in Children With Nonsyndromic Cleft Lip and Palate: A Prevalence Study

“…Blunden et al (2004) and Huang et al (2014) reported for the general pediatric population, at the same age range, rates of 5% and 13%, respectively, in studies also employing SDSC for OSA screening, reinforcing the importance of active screening and diagnosis of OSA in children with NSCLP. In addition, the present results are comparable to the findings of authors who also reported high frequency of OSA symptoms in children with CLP, between 15% and 53%, employing different sleep questionnaires (Muntz et al, 2008; MacLean et al, 2009; Robison and Otteson, 2011; MacLean et al, 2012; Cielo et al, 2014; Moraleda-Cibrián et al, 2014; Silvestre et al, 2014). The great variability between studies may reflect the heterogeneity of children with CLP analyzed and the different diagnostic criteria employed.…”

The correlation between OSA-related quality of life and two mental statuses in adolescent Chinese patients with cleft palate: A comprehensive study

“…According to OSA-18 results, we found that the average OSA-18 score of Chinese adolescent patients with CP was higher than the controls, which might reveal that adolescents with CP were at higher risk of OSA, consistent with the results evaluated by the Pediatric Sleep Questionnaire (PSQ) and polysomnography (PSG) in the previous studies (27,28). The rate of moderate or high impact of OSA on QoL in children with CP (8.7%), which was approximately consistent with previous studies (9.5%) (2), was significantly higher than that of the control group (0%).…”

Sleep Outcomes in Children with Single-Suture Craniosynostosis Compared with Unaffected Controls

“…Our study found a higher presence of parent-reported snoring among children aged 7 to 11 years with SSC compared with controls. Though preliminary, our results suggest that children with isolated SSC may have a higher risk for SDB, which is consistent with previous studies of other craniofacial anomalies (Cloonan et al, 2009;MacLean et al, 2009;Al-Saleh et al, 2011;Robison and Otteson, 2011;Plomp et al, 2012). To our knowledge, our study was the first to compare the occurrence of SDB between children with and without isolated SSC.…”

Symptoms of Obstructive Sleep Apnea, Nasal Obstruction, and Enuresis in Children With Nonsyndromic Cleft Lip and Palate: A Prevalence Study

“…Blunden et al (2004) and Huang et al (2014) reported for the general pediatric population, at the same age range, rates of 5% and 13%, respectively, in studies also employing SDSC for OSA screening, reinforcing the importance of active screening and diagnosis of OSA in children with NSCLP. In addition, the present results are comparable to the findings of authors who also reported high frequency of OSA symptoms in children with CLP, between 15% and 53%, employing different sleep questionnaires (Muntz et al, 2008; MacLean et al, 2009; Robison and Otteson, 2011; MacLean et al, 2012; Cielo et al, 2014; Moraleda-Cibrián et al, 2014; Silvestre et al, 2014). The great variability between studies may reflect the heterogeneity of children with CLP analyzed and the different diagnostic criteria employed.…”

The correlation between OSA-related quality of life and two mental statuses in adolescent Chinese patients with cleft palate: A comprehensive study

“…According to OSA-18 results, we found that the average OSA-18 score of Chinese adolescent patients with CP was higher than the controls, which might reveal that adolescents with CP were at higher risk of OSA, consistent with the results evaluated by the Pediatric Sleep Questionnaire (PSQ) and polysomnography (PSG) in the previous studies (27,28). The rate of moderate or high impact of OSA on QoL in children with CP (8.7%), which was approximately consistent with previous studies (9.5%) (2), was significantly higher than that of the control group (0%).…”

Sleep Outcomes in Children with Single-Suture Craniosynostosis Compared with Unaffected Controls

“…Our study found a higher presence of parent-reported snoring among children aged 7 to 11 years with SSC compared with controls. Though preliminary, our results suggest that children with isolated SSC may have a higher risk for SDB, which is consistent with previous studies of other craniofacial anomalies (Cloonan et al, 2009;MacLean et al, 2009;Al-Saleh et al, 2011;Robison and Otteson, 2011;Plomp et al, 2012). To our knowledge, our study was the first to compare the occurrence of SDB between children with and without isolated SSC.…”

Symptoms of Obstructive Sleep Apnea, Nasal Obstruction, and Enuresis in Children With Nonsyndromic Cleft Lip and Palate: A Prevalence Study

“…Blunden et al (2004) and Huang et al (2014) reported for the general pediatric population, at the same age range, rates of 5% and 13%, respectively, in studies also employing SDSC for OSA screening, reinforcing the importance of active screening and diagnosis of OSA in children with NSCLP. In addition, the present results are comparable to the findings of authors who also reported high frequency of OSA symptoms in children with CLP, between 15% and 53%, employing different sleep questionnaires (Muntz et al, 2008; MacLean et al, 2009; Robison and Otteson, 2011; MacLean et al, 2012; Cielo et al, 2014; Moraleda-Cibrián et al, 2014; Silvestre et al, 2014). The great variability between studies may reflect the heterogeneity of children with CLP analyzed and the different diagnostic criteria employed.…”

The correlation between OSA-related quality of life and two mental statuses in adolescent Chinese patients with cleft palate: A comprehensive study

“…According to OSA-18 results, we found that the average OSA-18 score of Chinese adolescent patients with CP was higher than the controls, which might reveal that adolescents with CP were at higher risk of OSA, consistent with the results evaluated by the Pediatric Sleep Questionnaire (PSQ) and polysomnography (PSG) in the previous studies (27,28). The rate of moderate or high impact of OSA on QoL in children with CP (8.7%), which was approximately consistent with previous studies (9.5%) (2), was significantly higher than that of the control group (0%).…”