2013
DOI: 10.1097/aog.0b013e3182a7e1f5
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Increased Pressure Pain Sensitivity in Women With Chronic Pelvic Pain

Abstract: OBJECTIVE To determine if women with chronic pelvic pain and variable degrees of endometriosis demonstrate altered pain sensitivity relative to pain-free healthy controls, and whether such differences are related to the presence or severity of endometriosis or comorbid pain syndromes. METHODS Four patient subgroups (endometriosis with chronic pelvic pain (n=42), endometriosis with dysmenorrhea (n=15), pain-free endometriosis (n=35), and chronic pelvic pain without endometriosis (n=22)) were each compared to … Show more

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Cited by 111 publications
(89 citation statements)
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References 26 publications
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“…Pressure pain sensitivity was evaluated at the thumbnail (As-Sanie et al, 2013; Giesecke et al, 2004; Petzke et al, 2001) using the Multimodal Automated Sensory Testing (MAST) system (Harte et al, 2013). The MAST system consists of a control computer that executes testing algorithms and stores testing data, and a touch-screen interface for participant feedback.…”
Section: Methodsmentioning
confidence: 99%
“…Pressure pain sensitivity was evaluated at the thumbnail (As-Sanie et al, 2013; Giesecke et al, 2004; Petzke et al, 2001) using the Multimodal Automated Sensory Testing (MAST) system (Harte et al, 2013). The MAST system consists of a control computer that executes testing algorithms and stores testing data, and a touch-screen interface for participant feedback.…”
Section: Methodsmentioning
confidence: 99%
“…Furthermore, chronic pelvic pain in endometriosis patients was associated with generalized hyperexcitability in the central nervous system [79], as well as a centrally mediated sensitization to pain in other peripheral areas [80]. It is therefore possible that a continued peripheral stimulation, coupled with the involvement of the central nervous system, will induce chronic pain that becomes independent of the lesion itself.…”
Section: Central Sensitization In Endometriosismentioning
confidence: 99%
“…Clinical manifestations of sensitization include regional allodynia and regional hyperalgesia (1113). Central and peripheral sensitization are reported in regional pain syndromes including endometriosis (14,15), migraine (16), fibromyalgia (17), painful bladder syndrome (18), irritable bowel syndrome (19), and overlapping pain conditions (20). …”
Section: Introductionmentioning
confidence: 99%