Increased non-attendance at epilepsy clinic in patients with neuropsychiatric comorbidities: A prospective study

Zertuche-Ortuño, Lizeth; Oropeza-Bustos, Nayeli; Crail-Meléndez, Daniel; Bribiesca-Contreras, Elisa; Martínez-Bustos, Verónica; Santos-Peyret, Andrea; Martínez-Medina, Salvador; Ochoa, Adriana; Jara‐Prado, Aurelio; Martínez‐Juárez, Iris E.

doi:10.1016/j.yebeh.2021.108202

Cited by 5 publications

(5 citation statements)

References 22 publications

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“…Endocrine, psychiatric, and respiratory comorbidities are associated with lower probability of achieving remission when adjusted for demographic and clinical variables [25 ▪▪ ]. Psychiatric comorbidities predispose individuals to a lack of response to antiseizure medication (ASMs), perhaps through poor adherence, in addition to discharge against medical advice and nonattendance at appointments, contributing to premature mortality [26,27 ▪ ,28 ▪ ]. Contrary to previous assumptions, ASMs are not associated with an increased risk of suicide [29], although there is clear evidence that having epilepsy, particularly of temporal lobe origin, increases the risk of committing suicide [30].…”

Section: The Burden Of Epilepsy Comorbiditiesmentioning

confidence: 99%

Learning from the comorbidities of epilepsy

Shlobin

Sander

2021

Current Opinion in Neurology

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Purpose of reviewComorbidities are a common feature in epilepsy, but neither the entire spectrum nor the significance of such comorbidities has been fully explored. We review comorbidities associated with epilepsy and their associated burden, provide an overview of relationships, and discuss a new conceptualization of the comorbidities.Recent findingsThe epidemiology of the comorbidities of epilepsy and effects on health outcomes, healthcare use, and healthcare expenditures have been partly delineated. Distinct mechanisms of the associations have been suggested but not entirely ascertained. Movement from conceptualizing epilepsy as a condition to a symptom-complex has occurred.SummaryComorbidities are common among people with epilepsy and are associated with poorer clinical outcomes and quality of life, greater use of health resources, and increased expenditure. Becoming aware of the associated mechanisms and their uncertainty is central to understanding the relationships between epilepsy and comorbid health conditions, which have implications for diagnosis and screening, medical management, and surgical management. Conceptualizing comorbidities of epilepsy as precipitating factors and epilepsy as the symptom will improve the understanding of epilepsy and catalyze research and improvements in clinical practice.

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Section: The Burden Of Epilepsy Comorbiditiesmentioning

confidence: 99%

Learning from the comorbidities of epilepsy

Shlobin

Sander

2021

Current Opinion in Neurology

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“…2,3 According to a previous study, depression in epilepsy results in uncontrolled seizures, lack of compliance to treatment, higher medical costs, and increased suicide rates. [4][5][6][7][8][9][10][11][12] Factors contributing to depression in PWE can be classified into individual, seizure-related, and social factors. [13][14][15] Epilepsy is still plagued by myths and prejudice, with some public exhibiting negative attitudes toward PWE.…”

Section: Introductionmentioning

confidence: 99%

Depression as comorbidity in Sundanese epilepsy patients

Tandiawan,

Gunadharma,

Gamayani

et al. 2023

NeuroAsia

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Background: Depressive disorder is a common psychiatric comorbidity in patients with epilepsy (PWE). This health condition is prevalent among the Sundanese who have a calm and polite character, with a tendency to hide their feelings, which is associated with an increased risk of depression. Methods: This cross-sectional study aimed to determine the prevalence of major depressive disorder (MDD) and the associated factors among Sundanese PWE. The study was carried out in the neurology outpatient clinic at Hasan Sadikin General Hospital Bandung, consisting of the Sunda ethnic group as the majority of patients. Self-stigma degree was measured using the Indonesian version of Internalized Stigma of Epilepsy (ISEP) questionnaire, while depression symptom was screened through the Indonesian version of Neurological Disorders Depression Inventory for Epilepsy (NDDI-E). Subsequently, patients who had depression symptoms were referred to a psychiatrist to confirm whether their conditions matched the criteria of MDD according to the Diagnostic and Statistical Manual of Mental Disorder-5. Results: The prevalence of depressive symptoms in Sundanese epilepsy patients was found to be 18.4%, and MDD was 6.8% among 103 patients included in this study. Many PWE with MDD were not married, had uncontrolled seizures, used polytherapy anti-seizure medication, and exhibited a higher degree of self-stigma. Conclusion: In this study, the prevalence of MDD was found to be 6.8% among a cohort of Sundanese PWE. A significant relationship was also observed between MDD and several factors, including single status, uncontrolled seizure, polytherapy, and a higher degree of self-stigma.

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“…The biobank DNA rate is consistently higher when compared to Wales and Health Board rates for all new outpatient and neurology clinics, but is comparable to DNA rates from Irish research. A 2018 study investigated non-attendance at Irish epilepsy outpatient clinics and found a DNA rate of 18.9%, while more recent research saw a rate of 17.9% (Haque, et al, 2018) and (Zertuche-Ortuño et al, 2021). A bespoke data request for this thesis, to NHS Wales Information Service provided missed appointment data for epilepsy clinics during the study period.…”

Section: Did Not Attend Ratementioning

confidence: 97%

“…A review by NHS Scotland (Campbell et al, 2015), and a study by (Zertuche-Ortuño et al, 2021), showed than more males than females did not attend their epilepsy appointments, in contrast to SNB data. However, data from NHS England between 2019 and 2020 indicated non-attenders were predominantly female, suggesting a variable picture exists (NHS England 2020).…”

Section: Did Not Attend Ratementioning

confidence: 99%

“…However, data from NHS England between 2019 and 2020 indicated non-attenders were predominantly female, suggesting a variable picture exists (NHS England 2020). What is clear, is that data from NHS Scotland and NHS England, as well as studies by (Zertuche-Ortuño et al, 2021) and (Minshall & Neligan, 2017), which specifically looked at epilepsy clinics, indicate that non-attenders are more likely to be younger compared to those who attend. The DNA group in the SNB are predominately females and younger than the mean age of the biobank participants.…”

Section: Did Not Attend Ratementioning

confidence: 99%

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Biobank participation of persons with epilepsy in South Wales

Baker

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Increased non-attendance at epilepsy clinic in patients with neuropsychiatric comorbidities: A prospective study

Cited by 5 publications

References 22 publications

Learning from the comorbidities of epilepsy

Learning from the comorbidities of epilepsy

Depression as comorbidity in Sundanese epilepsy patients

Biobank participation of persons with epilepsy in South Wales

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