Increased Mean Platelet Volume in Patients With Aortic Stenosis

Abstract

We have shown that MPV was significantly elevated in patients with AS compared to control participant.

Platelet indices in patients with infective endocarditis and embolic events; confounding factors should be considered

“…We believe that if the authors had considered the above-mentioned confounding factors, they would perhaps have found different results. Moreover, previous studies demonstrated that MPV was significantly elevated in patients with aortic and mitral stenosis compared to control subjects, possibly due to shear stress induced platelet activation [7,8]. However, the authors did not also mention the basal valvular status of the patients.…”

Mean Platelet Volume is Increased in Patients with Atrial Septal Aneurysm

“…It is known that platelets having dense granules are more active biochemically, functionally, and metabolically and are a risk factor for developing coronary and pulmonary thrombosis, leading to myocardial infarction. In previous studies, increased MPV was demonstrated in acute myocardial infarction [14,15], mitral and aortic stenosis [4,5], deep vein thrombosis [6], and hypertension [7]. The stroke in patient with ASA, platelet activation may play a considerable role.…”

“…Recent studies suggest that Mean Platelet Volume (MPV ) is a potentially useful prognostic biomarker in patients with cardiovascular disease such as acute coronary syndrom, valvular heart disease pulmonary thromboembolism and hypertension [4][5][6][7][8].…”

Mean platelet volume is increased in patients with chronic hepatitis B

“…It is known that platelets having dense granules are more active biochemically, functionally, and metabolically and are a risk factor for developing coronary and pulmonary thrombosis, leading to myocardial infarction. In previous studies, increased MPV was demonstrated in acute myocardial infarction [22,23], mitral and aortic stenosis [9,10], deep vein thrombosis [11], and hypertension [12].…”

“…Recent studies suggest that mean platelet volume (MPV) is a potentially useful prognostic biomarker in patients with cardiovascular disease such as acute coronary syndrome, valvular heart disease, pulmonary thromboembolism and hypertension [9][10][11][12].…”