Increased lung cancer mortality rates in the Chinese population from 1973‐1975 to 2004‐2005: An adverse health effect from exposure to smoking

Abstract

BACKGROUND: Lung cancer incidence and mortality rates have increased substantially in China despite improvements in clinical diagnosis and treatment approaches as well as significant advances in the implementation of tobacco-control policies in recent decades. METHODS: Age-standardized mortality rates and age-specific rates of lung cancer in China were estimated for the periods 1973 to 1975, 1990 to 1992, and 2004 to 2005 using data from 3 National Death Surveys. Among patients with lung cancer who were identified from a hospital-based information system, the percentages of ever-smokers were analyzed according to histologic and demographic variables. RESULTS: Age-standardized mortality from lung cancer in China dramatically increased from 7. [1973][1974][1975]. Among 6674 patients with lung cancer who were identified from 2003 to 2007 from a hospital-based database, 82.97% of men were ever-smokers (73.35% of men with adenocarcinoma and 91.8% of men with squamous cell carcinoma), and 11.18% of women were ever-smokers (6% of women with adenosquamous carcinoma and 39.02% of women with squamous cell carcinoma). Differences in the numbers of ever-smokers were observed between age groups but not according to the year of diagnosis. CONCLUSIONS: The consistent and rapid increases in lung cancer mortality rates observed in the Chinese population and the high prevalence of exposure to smoking in China prompt a strong call for the implementation of a comprehensive tobacco-control policy and specific public health educational strategies. Cancer 2015;121:3107-12.

Spatiotemporal Variations in Lung Cancer Mortality in China between 2006 and 2012: A Multilevel Analysis

“…This might indicate why lung cancer mortality is highest in the northeast. In addition, a high prevalence of exposure to smoking [23] and particulate matter air pollution [24] will have adverse health effects relevant to lung cancer mortality. This study did not include relevant data, and we will explore it in further research.…”

Smoking increases risks of all-cause and breast cancer specific mortality in breast cancer individuals: a dose-response meta-analysis of prospective cohort studies involving 39725 breast cancer cases

“…The non-linear curve on association of smoking duration and BC specific mortality risk showed relatively flat before 15 pack-years, and rose steeply after it. It was possibly explained that long time smoking was associated with increased mortality from other causes, such as lung cancer [24], cardiovascular events [25], cervical cancer [26], and so on [27]. …”

Circulating Free DNA in Serum and Genomic Alterations of Lung Cancer Patients and High Risk Individuals Exposed to Environmental Pollution

“…LC subjects from Antofagasta region showed a non-significant higher cfDNA levels than subjects from the Metropolitan region. In this context, is important to consider that in Antofagasta region a 73% (8) of the LC were SqCC and 18% [2] were AdC. On the other hand, in the Metropolitan region 19% (4) of the cases were SqCC and 67% (4) were AdC.…”

“…The LC mortality has dramatically increased in spite of several pharmacological and image technical advances [1,2]. The high incidence of LC has been associated with cigarette smoking, however genetic diversity and environmental pollution must also be considered as risk factors, especially in those cities highly exposed to environmental carcinogens.…”