Increased insula activity precedes the formation of subjective illusory Gestalt

Wilding, Marilena; Körner, Christof; Ischebeck, Anja; Zaretskaya, Natalia

doi:10.1016/j.neuroimage.2022.119289

Cited by 4 publications

(10 citation statements)

References 67 publications

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“…We first confirmed that our seed regions identified based on findings of our previous study ( Wilding et al 2022 ) engaged hypothesized intrinsic resting-state networks, as illustrated by the group connectivity results of each seed in Fig. 3 and Table 2 .…”

Section: Resultssupporting

confidence: 85%

“…Specifically, spontaneous activity in the human face-selective fusiform face area is higher if participants subsequently report perceiving a face in the ambiguous face-vase illusion ( Hesselmann et al 2008a ). In a recent fMRI study, we could demonstrate a similar effect using an asymmetric bistable stimulus with a global (illusory) and a local (non-illusory) interpretation (Anstis illusion, Anstis and Kim 2011 ; Wilding et al 2022 ). We found increased prestimulus insula and intraparietal sulcus (IPS) activity before participants perceived the global compared with the local interpretation.…”

Section: Introductionmentioning

confidence: 60%

“…Our previous study showed that a joint activity increase in the IPS and the insula precedes the subsequent global perception of an individual ( Wilding et al 2022 ), suggesting perception-related covariation of activity in the two areas. Therefore, in addition to performing a seed-based functional connectivity analysis for each seed separately, we performed the unshared functional connectivity analysis by adding time courses of both seeds into the same first-level GLM.…”

Section: Methodsmentioning

confidence: 96%

“…In order to determine the resting-state correlates of bistable perception, we computed seed-based RSFC with superior insula and anterior IPS as seeds, as we found these two regions to be relevant in our previous study ( Wilding et al 2022 ). Given that previous studies point to a right as well as left parietal involvement in bistable perception ( Zaretskaya et al 2013 ; Grassi et al 2016 ; Wilding et al 2022 ), we decided to use the average time series of the left and right IPS as our seed region. The anterior IPS was defined using the probabilistic atlas of visual topography (IPS5; Wang et al 2015 ).…”

Section: Methodsmentioning

confidence: 99%

“…In addition, we used the physiological signals recorded during the restingstate scan to account for physiological noise. Pulse and respiration signals were processed using the MATLAB-based PhysIO toolbox ( Kasper et al 2017 ) as described in our previous work ( Wilding et al 2022 ). In brief, the physiological data were aligned to the fMRI time series, preprocessed using a peak detection algorithm and subsequently RETROICOR phase expansion ( Glover et al 2000 ) was applied.…”

Section: Methodsmentioning

confidence: 99%

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Resting-state neural correlates of visual Gestalt experience

2023

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Subjective perceptual experience is influenced not only by bottom-up sensory information and experience-based top-down processes, but also by an individual’s current brain state. Specifically, a previous study found increased prestimulus insula and intraparietal sulcus (IPS) activity before participants perceived an illusory Gestalt (global) compared with the non-illusory (local) interpretation of a bistable stimulus. That study provided only a snapshot of the brain state that favors the illusory interpretation. In the current study, we tested whether areas that differentiate between the illusory and non-illusory perception, immediately before stimulus onset, are also associated with an individual’s general tendency to perceive it, which remains stable over time. We examined individual differences in task-free functional connectivity of insula and IPS and related them to differences in the individuals’ duration of the two stimulus interpretations. We found stronger connectivity of the IPS with areas of the default mode and visual networks to be associated with shorter local perceptual phases, i.e. a faster switch to an illusory percept, and an opposite effect for insula connectivity with the early visual cortex. Our findings suggest an important role of IPS and insula interactions with nodes of key intrinsic networks in forming a perceptual tendency toward illusory Gestalt perception.

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Section: Resultssupporting

confidence: 85%

Section: Introductionmentioning

confidence: 60%

Section: Methodsmentioning

confidence: 96%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Resting-state neural correlates of visual Gestalt experience

2023

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Conscious interpretation: A distinct aspect for the neural markers of the contents of consciousness

Bachmann

Aru

2023

Consciousness and Cognition

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Respiration recording for fMRI: breathing belt versus spine coil sensor

Wilding,

Ischebeck,

Zaretskaya

2023

Preprint

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Physiological signals such as pulse and respiration strongly contribute to non-neuronal signal change of the blood oxygenation level-dependent (BOLD) contrast in functional magnetic resonance imaging (fMRI). This has been observed not only during task-based but also during resting-state fMRI measurements, where the confounding influence of physiological signals is most pronounced. Over the last decades, a variety of techniques evolved, aiming at detecting and removing physiological artifacts in fMRI time series. These follow either a solely data-driven approach or rely on externally recorded physiological data. To record cardiac and respiratory signals, typically pulse oximetry or electrocardiography (ECG) and a respiration belt are used, respectively. New technologies allow to capture respiratory signal directly with a sensor placed within the spine coil in the patient table, eliminating the need of a respiration belt, which considerably increases participants comfort. However, little is known about the effectiveness of these new technologies and how they compare to the standard respiration belt recording. In the current study, we compared the two devices, respiration belt and spine coil sensor, in their suitability for physiological noise removal during a visual perception task and during rest. We did not find any differences in resting-state functional connectivity (RSFC) or stimulus-related activity between data corrected with the two recording devices. However, we did find reduced residual noise in the time series corrected with spine coil-derived respiration signals compared to belt-based corrected data in the task dataset. Our results show that spine coil- derived respiration recordings are slightly superior to belt respiration recordings for physiological noise removal in task-induced activity, with spine coil recordings having an additional advantage in terms of subject comfort.

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Increased insula activity precedes the formation of subjective illusory Gestalt

Cited by 4 publications

References 67 publications

Resting-state neural correlates of visual Gestalt experience

Resting-state neural correlates of visual Gestalt experience

Conscious interpretation: A distinct aspect for the neural markers of the contents of consciousness

Respiration recording for fMRI: breathing belt versus spine coil sensor

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