Increased HDL-C Values and Mortality: Revolutionizing a Historical Paradigm?

Lippi, Giuseppe; Sanchís-Gomar, Fabián; Lavie, Carl J.

doi:10.1055/s-0042-1753484

Semin Thromb Hemost

2022

DOI: 10.1055/s-0042-1753484

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Increased HDL-C Values and Mortality: Revolutionizing a Historical Paradigm?

Giuseppe Lippi

Fabián Sanchís-Gomar

Carl J. Lavie

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“…The issue concludes with a commentary on high-density lipoprotein cholesterol (HDL-C) and mortality 14 and some correspondence around cancer and thrombosis risk. 15 In the commentary, Lippi and colleagues discuss the latest findings, which indicate that contrary to established dogma, which dictate that high levels of HDL-C are associated with health benefits, that there may instead be a J - or U -shaped relationship.…”

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Celebrating 50 Years of Seminars in Thrombosis and Hemostasis—Part I

Favaloro

2022

Semin Thromb Hemost

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Welcome to another issue of Seminars in Thrombosis and Hemostasis (STH). This is a very special issue, being the first of a series of issues we will publish to celebrate the upcoming 50th anniversary of the journal. As explained more fully in an accompanying editorial, 1 STH has been part of the thrombosis and hemostasis landscape for almost 50 years. STH was first published in 1974, and so will turn 50 in 2024. As we head toward this landmark date, we believed it is appropriate to celebrate with a series of STH issues containing content of a somewhat historical nature. The current issue of STH, the last for 2022, marks the first of these issues. We are not yet 50, but we are getting close.STH was founded by Eberhard F. Mammen (►Fig. 1). The journal started small, with only two issues and some 210 printed pages in its first year. The journal has grown over the years, and now publishes eight issues, and some 900 printed pages, per year, having also achieved a landmark of more than 1,000 printed pages in 2020.This issue contains a range of material related to the broad concepts of thrombosis and hemostasis and with a historical connection. The issue begins with two articles on fibrinogen, the major clotting protein in blood. The first, by Casini and colleagues, is a true historical piece that celebrates a 100year history of investigation into congenital fibrinogen disorders, but focusing mostly on afibrinogenemia and dysfibrinogenemia. 2 These disorders encompass a broad range of fibrinogen defects characterized by a wide molecular and clinical spectrum. From the first clinical description of afibrinogenemia in 1920, the authors describe the many major achievements that have contributed to a better understanding of these complex disorders. The finding of causative

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Celebrating 50 Years of Seminars in Thrombosis and Hemostasis—Part I

Favaloro

2022

Semin Thromb Hemost

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The associations between exercise and lipid biomarkers

Sulague

Suan

Mendoza³

et al. 2022

Progress in Cardiovascular Diseases

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Increased HDL-C Values and Mortality: Revolutionizing a Historical Paradigm?

Cited by 2 publications

References 29 publications

Celebrating 50 Years of Seminars in Thrombosis and Hemostasis—Part I

Celebrating 50 Years of Seminars in Thrombosis and Hemostasis—Part I

The associations between exercise and lipid biomarkers

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