Abstract:The hemopoietic events in the embryonic mouse spleen were investigated in fetuses of polycythemic mothers. 12th and 13th day embryonic spleens showed a marked increase in the number of erythroid precursors at an advanced maturation stage, as compared to controls. In addition, an increased erythropoietic activity, measured by 59Fe incorporation into red blood cells of posthypoxic polycythemic mice, was found in the plasma of 12th and 13th day pregnant polycythemic mice, compared with controls, i.e. p… Show more
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