Increased Enamel Hypoplasia and Very Low Birthweight Infants

Nelson, Suchitra; Albert, Jeffrey M.; Geng, Cuiyu; Curtan, Shelley; Lang, Katrin; Miadich, S.; Heima, Masahiro; Malik, Anchal; Ferretti, Gerald A.; Eggertsson, Hafsteinn; Slayton, Rebecca L.; Milgrom, Peter

doi:10.1177/0022034513497751

Cited by 53 publications

(72 citation statements)

References 19 publications

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“…In the literature, LBW was not associated with dental caries in the primary dentition [Shulman, 2005;Tanaka and Miyake, 2014;Nirunsittirat et al, 2016]. The association between LBW and DDE found in other studies [Lunardelli and Peres, 2006;Ferrini et al, 2008;Velló et al, 2010;Takaoka et al, 2011;Cruvinel et al, 2012;Masumo et al, 2013;Nelson et al, 2013;Elfrink et al, 2014] was confirmed by the present data. Although in the literature mainly hypoplasia was associated with LBW [Aine et al, 2000;Velló et al, 2010;Masumo et al, 2013], in our study all types of DDE were associated with LBW.…”

Section: Risk Factorssupporting

confidence: 89%

“…This might have contributed to reaching also families with a low or moderate health care compliance. Furthermore, the highest prevalence of DDE (90.0%) occurred in PTI with ELBW, which confirms previous observations that ELBW is associated with a high prevalence of DDE in the primary dentition [Ferrini et al, 2008;Cruvinel et al, 2012;Correa-Faria et al, 2013;Masumo et al, 2013;Nelson et al, 2013;Elfrink et al, 2014]. In the PTI-G significantly more tooth surfaces were affected by all types of DDE and the highest occurrence was recorded in PTI with ELBW.…”

Section: Dental Cariessupporting

confidence: 87%

“…The PTI-G had a lower SES than the FTI-G, so the higher prevalence and experience of dental caries in the PTI-G might to some extent be due to the lower SES in that group. A lower SES was associated with a higher rate of DDE only in the FTI-G, confirming the results of Cruvinel [2012] and Nelson [2013], but not in the PTI-G, in agreement with Elfrink [2014].…”

Section: Risk Factorssupporting

confidence: 86%

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Dental Caries and Developmental Defects of Enamel in the Primary Dentition of Preterm Infants: Case-Control Observational Study

Schüler

Haberstroh²,

Dawczynski³

et al. 2017

Caries Res

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Aim: Assessment of dental health in the primary dentition of preterm infants (PTI) including investigation of mother- and infant-related risk factors in a case-control study design. Material and Methods: One hundred twenty-eight infants aged 3-4 years were included. Sixty-four PTI (27 males) were randomly selected from the preterm registry of the Jena University Hospital. As a control group served 64 full-term infants (FTI) recruited from the Department of Paediatric Dentistry, matched for age and sex. Dental examinations were provided by one dentist under standard clinical conditions. Caries was scored using the International Caries Detection and Assessment System (ICDAS II) and the DMFT, gingival health using the Periodontal Screening Index, and developmental defects of enamel using the DDE index. Mother- and infant-related factors were collected via a questionnaire and from medical records. Results: The caries prevalence was 50.0% (ICDAS II >0) in PTI and 12.5% (ICDAS II >0) in FTI. The caries experience was higher in PTI (DMFT 1.0 ± 3.1) than in FTI (DMFT 0.3 ± 1.0). PTI had a higher risk of caries (OR 7.0), initial lesions (OR 6.2), DDE (OR 7.5), and gingivitis (OR 6.5) than FTI. The highest risk occurred in PTI with an extremely low birth weight (<1,000 g). A higher risk of DDE was present when mothers suffered from illness during pregnancy (OR 3.9). A higher risk of caries was revealed in infants with respiratory syndrome (OR 6.2) or when their mothers had a lower socioeconomic status (OR 6.3). Conclusions: PTI had less healthy teeth than FTI and are at a higher risk for DDE, caries, and gingivitis. The poorer dental health in PTI is associated with a low birth weight, a low socioeconomic status, and mothers' illness during pregnancy.

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Section: Risk Factorssupporting

confidence: 89%

Section: Dental Cariessupporting

confidence: 87%

Section: Risk Factorssupporting

confidence: 86%

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Dental Caries and Developmental Defects of Enamel in the Primary Dentition of Preterm Infants: Case-Control Observational Study

Schüler

Haberstroh²,

Dawczynski³

et al. 2017

Caries Res

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“…Enamel hypoplasia is linked to celiac disease in some patients (Smith and Miller 1979;Wierink et al 2007) but as a non-specific stress indicator. It is also linked to environmental and societal stressors such as food shortage (Geber 2014), weaning (Ash et al 2016) and birth weight (Nelson et al 2013). Enamel hypoplasia can also be a hereditary condition (Robinson, Miller, and Worth1966).…”

Section: Celiac Disease Inferred From Pathological Morphologymentioning

confidence: 99%

Gluten-Free Rome: Celiac disease in the bioarchaeological record

Simpson

2017

SAJA

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Celiac disease, an autoimmune disorder triggered by consumption of the gluten protein, is theorized to have originated alongside the domestication of wheat during the European Agricultural Revolution, ca. 8 000 BCE (Freeman 2013). Human conditions that primarily affect soft tissue, like celiac disease, do not leave tangible evidence on the skeleton and therefore it is difficult to prove their presence. However, recent analyses have employed a suite of macroscopic, molecular, and chemical techniques to establish that a Roman Imperial (100–300 CE) individual from Cosa, Italy, likely suffered from celiac disease. This paper analyzes the works of these researchers and argues that this case study exemplifies modern bioarchaeology, which frequently requires an arsenal of methods beyond visual observation. Using similar syntheses of techniques bioarchaeologists can possibly identify celiac disease in individuals predating 100 CE, recreating the origins of celiac disease as well as tackling other previously ‘impossible’ research questions in this field.

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“…[5]Also studies have revealed a reduction in the caries activity in children whose mothers used xylitol products [6,7] as xylitol significantly reduces the levels of mutans streptococci by disrupting the energy production processes leading to a futile energy consumption cycle and cell death. [6][7][8] Preterm infants and infants with very low birth weight experience a higher incidence of enamel (tooth) defects and enamel hypoplasia [9]. Periodontal disease has been linked to preterm labour [10].…”

Section: Introductionmentioning

confidence: 99%