2015
DOI: 10.1111/anu.12238
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Increased dietary phosphorous prevents vertebral deformities in triploid Atlantic salmon (Salmo salarL.)

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Cited by 82 publications
(152 citation statements)
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“…Alp and mmp13 are responsible for bone formation and mineralisation and cartilage and bone resorption, respectively [7379]. In Atlantic salmon, all these genes have been already shown to be differential expressed in poorly mineralised and deformed vertebrae relative to normal vertebrae [8, 80, 81]. The current study suggests their involvement in the development of a skeletal anomaly affecting the lower jaw in Atlantic salmon.…”
Section: Discussionmentioning
confidence: 59%
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“…Alp and mmp13 are responsible for bone formation and mineralisation and cartilage and bone resorption, respectively [7379]. In Atlantic salmon, all these genes have been already shown to be differential expressed in poorly mineralised and deformed vertebrae relative to normal vertebrae [8, 80, 81]. The current study suggests their involvement in the development of a skeletal anomaly affecting the lower jaw in Atlantic salmon.…”
Section: Discussionmentioning
confidence: 59%
“…In support of a possible hormonal involvement in the condition, LJD has been recently linked to dietary phosphorus (P) deficiency during early stages of development in Atlantic salmon and different dietary P physiological requirements of triploids compared to diploids [8]. As bone in particular and the skeleton in general have a key role in endocrine regulation of minerals and nutrients [43], the onset of LJD could be either the result of a pre-existing impairment in the hormonal pathways of phosphate regulation, possibly involving gphb5 as a thyrostimulin, or that different physiological P requirements, especially in triploids, and dietary P deficiency may trigger or facilitate LJD onset with the effect displayed in the differential expression of particular genes involved in phosphate hormonal control, with a possible role for gphb5 as a thyrostimulin.…”
Section: Discussionmentioning
confidence: 99%
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“…Phosphorus levels in feed up to 16 mg/kg have been shown to prevent vertebral deformities (Fjelldal et al., ). This was not borne out by our study, in which dietary phosphorus ranged from 12.0 to 17.7 mg/kg.…”
Section: Nutritional Composition Of Biomar Feed (Manufacturer's Data)mentioning
confidence: 99%