Increased costs due to inappropriate surgical antibiotic prophylaxis in a university hospital

Yalcin, Ata Nevzat; Serin, Salih; Erbay, Hakan; Tomatir, Erkan; Öner, Özlem; Turgut, Hüseyin

doi:10.1053/jhin.2002.1289

Cited by 11 publications

(6 citation statements)

References 7 publications

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“…Al-Ghamdi et al 9 in Saudi Arabia reported a minimum government cost of US$565,603 annually for misused antibiotics. According to surveys by other investigators in Belgium 7 and Turkey, 6 adherance to guideline recommendations decreases extra costs associated with inappropriate use of antibiotic prophylaxis. Although antimicrobial prophylaxis can decrease the incidence of SSI, this benefit must be weighed against the risks of adverse drug reactions, the emergence of resistant bacteria, and the direct monetary cost.…”

Section: Discussionmentioning

confidence: 99%

Adherence to American Society of Health-System Pharmacists Surgical Antibiotic Prophylaxis Guidelines in Iran

Askarian

Moravveji

Mirkhani

et al. 2006

Infect. Control Hosp. Epidemiol.

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We assessed the appropriateness of surgical antibiotic prophylaxis in 6 teaching hospitals in Shiraz, Iran, using the American Society of Health-System Pharmacists guideline as a reference. We reviewed the medical records of 1,000 patients who underwent 1 of 9 different surgical procedures (1 procedure per patient). The proportion of procedures in which there was compliance with all guideline recommendations was 0.3%. The most common mistakes were overuse and misuse of antibiotics.

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Section: Discussionmentioning

confidence: 99%

Adherence to American Society of Health-System Pharmacists Surgical Antibiotic Prophylaxis Guidelines in Iran

Askarian

Moravveji

Mirkhani

et al. 2006

Infect. Control Hosp. Epidemiol.

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“…Thus, a cost effective perioperative antibiotic protocol is needed. 15 Timing of antimicrobial prophylaxis is the most important factor for the prevention of surgical infections.…”

Section: Discussionmentioning

confidence: 99%

Study of efficacy of short course peri-operative antibiotics in clean contaminated surgeries

Shivakumar¹,

Shoeb²,

Pinate³

2017

Int Surg J

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Background: Surgical site infection is a one of the most common postoperative complication and causes significant postoperative morbidity and mortality. WHO described Hospital acquired infections as one of the major infectious diseases having huge economic impact. Perioperative antibiotics constitute the bulk of antimicrobial consumption in any hospital. We need to adapt the policies that decrease the incidence of postoperative wound infection.Methods: Patients undergoing elective surgeries for clean contaminated cases for various causes from 15th May 2014 to 15th June 2017 under Surgical 1st Unit of District hospital Gulbarga (Affiliated to Gulbarga Institute of Medical Sciences, Gulbarga) are included in our study. During this period, a total of 216 patients participated, of which 145 were males and 71 were females. Patients received two doses of perioperative antibiotics, first dose before surgery and second dose after surgery, 12 hours apart during this period.Results: In this study, surgical site infection rate is 2.3% in clean-contaminated surgeries.Conclusions: The findings indicate that a short course of perioperative antibiotics where in first dose is given 30 minutes to one hour before surgery and second dose is given 12 hours after surgery are sufficient and efficacious as infection rate is acceptable (1%-3%).Infection rate in our study was 2.3%. It is cost-effective as well for prevention of surgical site infections in clean-contaminated surgeries in Indian surgical setup.

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“…Consequently, first generation cephalosporins, such as cefazolin, are the suggested first choice drugs [21,24,29]. Several studies show that the implementation of antibiotic prophylaxis is still extremely variable, despite the presence of national, regional and local GLs; antibiotics are used excessively and often inappropriately [30][31][32][33][34][35].…”

Section: Discussionmentioning

confidence: 99%

Reinforcing good practice: Implementation of guidelines at hospital G. Pini

Nobile

Bronzin

Navone

et al. 2014

Injury

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Increased costs due to inappropriate surgical antibiotic prophylaxis in a university hospital

Cited by 11 publications

References 7 publications

Adherence to American Society of Health-System Pharmacists Surgical Antibiotic Prophylaxis Guidelines in Iran

Adherence to American Society of Health-System Pharmacists Surgical Antibiotic Prophylaxis Guidelines in Iran

Study of efficacy of short course peri-operative antibiotics in clean contaminated surgeries

Reinforcing good practice: Implementation of guidelines at hospital G. Pini

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