Increased Concentration of Free Fatty Acids in Liver Disease.

Stormont, James M.; Mackie, Joseph E.; Davidson, Charles S.

doi:10.3181/00379727-106-26428

Cited by 77 publications

(2 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Liver diseases such as hepatitis, cirrhosis and hepatic coma lead to a significant increase of free fatty acids in serum, especially oleic acid [9,19,32,37], which are thought not to be absorbed from liver parenchyma. The amount of liver fat has not been taken into consideration in those studies.…”

Section: Discussionmentioning

confidence: 99%

The fatty acid pattern of adipose tissue and liver triglycerides according to fat droplet size in liver parenchymal cells of diabetic subjects

et al. 1974

View full text Add to dashboard Cite

111 40 diabetic inpatients the fatty acid pattern of triglycerides in liver Iat and in subcutaneous adipose tissue was determined by gas liquid chromatography. With rising size oI fat droplets in liver parenehyreal cells there was a significant increase of palmitic acid (C:16), oleic acid (C 18: 1) and linoleie acid (C 18:2) as well as a decrease of myristoleic acid (C 14 : 1), araehidonic (C 20:4) and eieosapentaenoie acid (C 20:5) in liver tri-glyeerides, resulting in a fatty acid composition in big droplets similar to that of adipose tissue. Fatty acid pattern of subcutaneous depot fat was strikingly constant.

show abstract

Section: Discussionmentioning

confidence: 99%

The fatty acid pattern of adipose tissue and liver triglycerides according to fat droplet size in liver parenchymal cells of diabetic subjects

et al. 1974

View full text Add to dashboard Cite

show abstract

“…Wherever liver function was damaged in animal ex periments (hepatectomy, poisoning of liver cells) or in human dis eases, it was followed by disturbances in the fat metabolism. The FFA are a specially sensitive indicator, since their level increases dur ing such disturbances as already has been proved by Wajckenberg et al [22] and also by Havel and Goldfien [11] and Stormont et al [20]. In the course of hepatitis, too, the increased level of FFA decreases simultaneously with an improvement in the condition of the patient [21].…”

Section: Discussionmentioning

confidence: 89%

Bile Salts and Lipolysis

Stork¹,

Fabian²,

Sponarová³

1968

Enzymol Biol Clin

View full text Add to dashboard Cite

Summary. The free fatty acid level was significantly reduced (P < 0.001) after intravenous administration of 10 ml of a 20% solution of sodium dehydrocholate. The activity of the postheparin lipoprotein lipase was equally significantly reduced after an injection of this compound (P < 0.001). The addition of 2.10-7 mol per 1 ml sodium dehydrocholate to the substrate mixture with postheparin plasma in vitro, reduced the lipoprotein lipase just as significantly (P < 0.001). It is thus possible that the decrease in lipacidaemia after dehydrocholate is caused by the inhibition of the lipolysis.

show abstract

Introduction—a perspective

Wertheimer

1965

Comprehensive Physiology

View full text Add to dashboard Cite

Increased Concentration of Free Fatty Acids in Liver Disease.

Cited by 77 publications

References 4 publications

The fatty acid pattern of adipose tissue and liver triglycerides according to fat droplet size in liver parenchymal cells of diabetic subjects

The fatty acid pattern of adipose tissue and liver triglycerides according to fat droplet size in liver parenchymal cells of diabetic subjects

Bile Salts and Lipolysis

Introduction—a perspective

Contact Info

Product

Resources

About