Increased Cardio-ankle Vascular Index in Hyperlipidemic Patients without Diabetes or Hypertension

Abstract

The present findings demonstrated that dyslipidemia increases the CAVI values in comparison to that seen in healthy subjects.

Cardio-Ankle Vascular Index is Independently Associated with Future Cardiovascular Events in Outpatients with Metabolic Disorders

“…Furthermore, no special technique is required for the measurement of CAVI. Indeed, CAVI has been associated with a number of risk factors for cardiovascular disease and the severity of CVD 10,[12][13][14][15] . An increase in the number of risk factors for metabolic syndrome was also positively correlated with an increased CAVI, probably due to insulin resistance 16) .…”

Frequency of coronary artery stenosis in patients with asymptomatic familial hypercholesterolemia and its association with carotid intimal thickness and cardio-ankle vascular index

“…On the other hand, another study showed that a significant increase in CAVI was observed in patients with combined hyperlipidemia who had a low (,40 mg/dL) HDL-cholesterol level but not in patients with hypercholesterolemia alone. 40 These findings suggested that CAVI may increase when both increased LDL-cholesterol level and decreased HDL-cholesterol level were observed.…”

Hypercholesterolemia and Hypertension: Two Sides of the Same Coin

“…Different ultrasonographic methods revealed that hypertension was associated with increases in arterial stiffness, whereas investigators found a higher prevalence and severity of carotid atherosclerosis in patients with hypercholesterolemia additional to arterial stiffness change. Recently, Dobsak et al [28] reported that the cardio-ankle vascular index, a sensitive non-invasive marker of arterial stiffness and atherosclerosis, was significantly increased in normotensive patients with hyperlipidemia (primary hypercholesterolemia, combined hyperlipidemia). Furthermore, Kanaki et al [29] showed that low-dose atorvastatin treatment improved arterial stiffness and exerted a reduction on central aortic pressures in patients with mild hypertension and hypercholesterolemia [29].…”