Increased brain and behavioural susceptibility to portion size in children with loss of control eating

Masterson, Travis D.; Fearnbach, S. Nicole; Tanofsky‐Kraff, Marian; Fisher, Jennifer O.; Wilson, Stephen J.; Rolls, Barbara J.; Keller, Kathleen L.

doi:10.1111/ijpo.12436

Cited by 19 publications

(18 citation statements)

References 78 publications

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“…These heightened expectations may also be maintained and exacerbated by elevated taste responsiveness, which may initiate a vicious cycle that elevates risk for disinhibited eating behaviors, such as LOC eating (Berridge, 2009). Supporting this notion are findings showing that children with LOC eating exhibit greater neural activation to highly palatable food cues compared with children without LOC eating (English et al, 2019). A number of other reward-based constructs, such as the reinforcing value of food and food addiction, warrant study in relation to LOC eating to elucidate which youth may be predisposed to develop adult BED and obesity.…”

Section: Reward Responsivitymentioning

confidence: 99%

A developmental framework of binge-eating disorder based on pediatric loss of control eating.

Tanofsky‐Kraff¹,

Schvey²,

Grilo³

2020

American Psychologist

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Although binge-eating disorder may manifest in childhood, a significantly larger proportion of youth report episodes involving a loss of control while eating, the hallmark feature of binge eating that predicts excess weight gain and obesity. Adults with binge-eating disorder often report that symptoms emerged during childhood or adolescence, suggesting that a developmental perspective of binge eating may be warranted. Thus, loss of control eating may be a marker of prodromal binge-eating disorder among certain susceptible youth. The present article offers a broad developmental framework of binge-eating disorder and proposes areas of future research to determine which youths with loss of control eating are at risk for persistent and exacerbated behavior that may develop into binge-eating disorder and adult obesity. To this end, this article provides an overview of loss of control eating in childhood and adolescence, including its characterization, etiology, and clinical significance, with a particular focus on associations with metabolic risk, weight gain, and obesity. A conceptual model is proposed to further elucidate the mechanisms that may play a role in determining which youths with loss of control are at greatest risk for binge-eating disorder and obesity. Ways in which treatments for adult binge-eating disorder may inform approaches to reduce loss of control eating and prevent excess weight gain in youth are discussed.

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Section: Reward Responsivitymentioning

confidence: 99%

A developmental framework of binge-eating disorder based on pediatric loss of control eating.

Tanofsky‐Kraff¹,

Schvey²,

Grilo³

2020

American Psychologist

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“…A possible way physical activity may affect eating behaviors is through cognitive processes that are related to food intake. Neuroimaging studies provide quantitative measurements of neural correlates of appetite and food intake (English et al., 2019; Hollman et al., 2012; Holsen et al., 2005; Masterson et al., 2018). For example, studies using functional magnetic resonance imaging (fMRI) report that acute bouts of physical activity reduce neural responses to images of food in reward regions of the brain and increases activity to high‐calorie, compared to low‐calorie, images potentially suggesting increased inhibition or food‐related cognitive control (Evero et al., 2012; Masterson et al., 2018).…”

Section: Introductionmentioning

confidence: 99%

To play or not to play? The relationship between active video game play and electrophysiological indices of food‐related inhibitory control in adolescents

Smith

Carbine

Larson

et al. 2020

Eur J of Neuroscience

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Sedentary behaviors, such as computer use and sedentary video games, are barriers to physical activity, contribute to overweight and obesity among adolescents, and can adversely affect eating behaviors. Active video games may increase daily physical activity levels among adolescents and improve food‐related inhibitory control. We compared the effects of acute bouts of active and sedentary video gaming on event‐related potential (ERP) indices of food‐related inhibitory control, energy expenditure, and ad libitum eating. In a within‐subjects design, 59 adolescent participants (49% female, Mage = 13.29 ± 1.15) completed two separate counterbalanced, 60‐min long video gaming sessions separated by seven days. Immediately after, participants completed two go/no‐go tasks with high‐ and low‐calorie images and N2 and P3 ERP amplitudes were measured. Participants also completed a Stroop task and were given high‐ and low‐calorie snacks to consume ad libitum. Results indicated that active relative to sedentary video games significantly increased energy expenditure on multiple measures (e.g., METs, heart rate, kcals burned) and participants consumed more calories after the active compared to the sedentary video game session. N2 amplitudes were larger when participants inhibited to high‐ compared to low‐calorie foods, suggesting that high‐calorie foods necessitate increased the recruitment of inhibitory control resources; however, there were non‐significant differences for the N2 or P3 amplitudes, accuracy or response times, and Stroop performance between active versus sedentary video game sessions. Overall, sixty minutes of active video gaming increased energy expenditure and food consumption but did not significantly alter neural or behavioral measures of inhibitory control to food stimuli.

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“…Alternatively, inconsistencies may be the result of differences in questionnaire format. Future longitudinal designs should assess whether youth who report LOC‐eating presence on the LOC‐ED‐Q are at heightened risk for weight gain or metabolic complications, compared with those who report LOC‐eating on the QEWP‐C‐5, and to elucidate previously observed differences in outcomes based on LOC‐eating presence as reported on the LOC‐ED‐Q (English et al, ; Mazzeo et al, ). Consistent with hypotheses, all three measures were associated with greater depressive and anxiety symptoms.…”

Section: Discussionmentioning

confidence: 99%

“…Constructs assessed by the LOC‐ED‐Q were based on a multisite study that elucidated the behavioral, contextual and emotional correlates of LOC‐eating (Tanofsky‐Kraff et al, ) in order to improve upon prior inadequate measures of LOC‐eating in youth. Two studies have used the LOC‐ED‐Q to assess the presence of LOC‐eating (English et al, ; Mazzeo et al, ). English et al () found that youth with LOC‐eating as identified by the LOC‐ED‐Q showed increased susceptibility to overeating in response to large portions, and using fMRI, found that such children showed greater cerebellar activation when responding to food cues compared with those who did not report LOC.…”

Section: Introductionmentioning

confidence: 99%

“…Two studies have used the LOC‐ED‐Q to assess the presence of LOC‐eating (English et al, ; Mazzeo et al, ). English et al () found that youth with LOC‐eating as identified by the LOC‐ED‐Q showed increased susceptibility to overeating in response to large portions, and using fMRI, found that such children showed greater cerebellar activation when responding to food cues compared with those who did not report LOC. Mazzeo et al () evaluated two interventions to target disordered‐eating behaviors, and found both reduced LOC‐eating based on the LOC‐ED‐Q.…”

Section: Introductionmentioning

confidence: 99%

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Assessment of loss‐of‐control eating in healthy youth by interview and questionnaire

Altman

Tanofsky‐Kraff

Shank

et al. 2020

Intl J Eating Disorders

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Objective: The aim of this study is to evaluate two questionnaires, an updated youth version of the questionnaire on eating and weight patterns (Questionnaire on Eating and Weight Patterns-5 Children/Adolescent [QEWP-C-5]) and the Loss-of-Control (LOC) Eating Disorder Questionnaire (LOC-ED-Q), against the Eating Disorder Examination (EDE) interview to assess the presence of LOC-eating among youth. Method: Two-hundred and eighteen youths (12.8 ± 2.7 years) completed the QEWP-C-5, LOC-ED-Q, and EDE, depressive and anxiety questionnaires, and adiposity assessment. Sensitivity, specificity, positive-predictive value, negativepredictive value, and diagnostic accuracy were calculated; Cochran's Q and McNemar's tests were used to compare measures. Receiver operating characteristic area under the curve (AUC) analyses were performed. Mood and adiposity based on LOC-eating presence and absence based on each measure were examined.Results: The QEWP-C-5 and LOC-ED-Q demonstrated poor sensitivity (33%; 30%) and high specificity (95%; 96%) compared with the EDE. The AUCs suggested neither the QEWP-C-5 (0.64) nor the LOC-ED-Q (0.62) demonstrated acceptable diagnostic accuracy. Comparing distributions of LOC-eating presence between assessments, the QEWP-C-5 and EDE did not differ significantly (p = .10), while the LOC-ED-Q and Trial Registration: ClinicalTrials.gov ID#: NCT02390765. /journal/eat EDE had significantly different distributions (p = .03). LOC-eating presence was associated with higher depressive and anxiety symptoms across all measures (ps < .02).Greater adiposity (ps < .02) was associated with LOC-eating presence on the EDE and LOC-ED-Q, and higher BMI z-score (p = .02) on the LOC-ED-Q.Discussion: Neither the QEWP-C-5 nor the LOC-ED-Q was sensitive for identifying LOC-eating presence as determined by the EDE, although both were associated with greater mood symptoms. Research is needed to improve self-report questionnaires to better screen for LOC-eating presence among pediatric populations. K E Y W O R D S adiposity, adolescents, assessment, children, loss-of-control eating

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Increased brain and behavioural susceptibility to portion size in children with loss of control eating

Abstract: Children who reported LOC were more susceptible to the PSE and showed alterations in food-cue processing in the cerebellum, a hindbrain region implicated in satiety signalling.

Cited by 19 publications

References 78 publications

A developmental framework of binge-eating disorder based on pediatric loss of control eating.

A developmental framework of binge-eating disorder based on pediatric loss of control eating.

To play or not to play? The relationship between active video game play and electrophysiological indices of food‐related inhibitory control in adolescents

Assessment of loss‐of‐control eating in healthy youth by interview and questionnaire

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