Increased brachial-ankle pulse wave velocity is associated with impaired endothelial function in patients with coronary artery disease

Dh, Liu; Wang, Y; Xx, Liao; Mg, Xu; Jm, Wang; Yang, Zhaohui; Chen, L; Lu, Jiwen; Lü, Kun; Jiang, Tao

doi:10.1097/00029330-200611020-00004

Cited by 14 publications

(11 citation statements)

References 18 publications

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“…After subjects had rested in a supine position for C15 min, brachial-ankle pulse wave velocity (baPWV) was measured in accordance with previously reported methods [2,[43][44][45][46]. PWV, arterial BP, electrocardiography (ECG), heart sounds, and HR were measured using a semiautomated device (form PWV/ABI; Colin Medical Technology, Japan).…”

Section: Assessment Of Arterial Stiffnessmentioning

confidence: 99%

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Vascular adaptations to hypobaric hypoxic training in postmenopausal women

et al. 2010

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The objective of this study was to examine the effects of exercise training in hypoxia on arterial stiffness and flow-mediated vasodilation (FMD) in postmenopausal women. Sixteen postmenopausal women (56±1 years) were assigned to a normoxic exercise group (Normoxic group, n=8) or a hypoxic exercise group (Hypoxic group, n=8). The Hypoxic group performed exercise under hypobaric hypoxic conditions corresponding to 2000 m above sea level, and was exposed to these conditions for 2 h per session. Aquatic exercise was performed at an intensity of around 50% peak oxygen uptake for 30min, 4days per week, for 8 weeks. Arterial stiffness was assessed by brachial-ankle pulse wave velocity (baPWV), and FMD was evaluated by peak diameter of the popliteal artery during reactive hyperemia. After the 8 weeks of training, the Normoxic group showed no significant changes. In contrast, baPWV (P < 0.05) was significantly reduced and peak diameter (P<0.05) and %FMD (P<0.01) were significantly increased in the Hypoxic group after training. These results suggest that exercise training under mild intermittent hypoxic conditions could more effectively reduce arterial stiffness in postmenopausal women, compared with exercise training performed at the same relative intensity under normoxic conditions. Our data also indicate that hypoxic exercise training may induce vascular functional adaptation, for example an increase in FMD response. These findings therefore could have important implications for the development of a new effective exercise prescription program.

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Section: Assessment Of Arterial Stiffnessmentioning

confidence: 99%

“…Pass lengths between the arm and ankle were calculated automatically according to the height of the subject [46]. The mean of left and right baPWV in each subject was used for subsequent analyses [44]. In our laboratory, the day-to-day coefficient of variation was 2.7 ± 0.3% for baPWV.…”

Section: Assessment Of Arterial Stiffnessmentioning

confidence: 99%

Vascular adaptations to hypobaric hypoxic training in postmenopausal women

et al. 2010

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“…Parameter b/a can be used for assessing AS changes during a single measurement and dynamic range of the artery wall elastic properties. LAS was also calculated by the equation (2) of the proved distensibility coefficient (DC) method [7], and compared with the results obtained from the PPG signal analysis, where ( 2 ) where DC is distensibility coefficient, Δd -amplitude of artery diameter pulsations, PP -difference between systolic and diastolic pressure, obtained by beat-per beat pressure monitor. The amplitude of the artery diameter pulsations greatly depends on the precise selection of observed segment of artery.…”

Section: Calculationsmentioning

confidence: 99%

“…Currently, arterial dysfunction is mostly assessed by mechanical -pressure cuff based plethysmography methods [2]. Meanwhile our interest is focused on developing both devices and software to assess usability of photoplethysmography (PPG), and prove its stability and reliability in detection of AS changes.…”

Section: Introductionmentioning

confidence: 99%

Usability of photoplethysmography method in estimation of conduit artery stiffness

et al. 2011

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Three channel photoplethysmography (PPG) signal waveform studies of leg conduit arteries during a provocative occlusion test were performed. PPG waveform second derivative amplitude ratio and arterial pulse wave velocity values showed significant correlations with ultrasound (US) reference method of local and regional arterial stiffness (AS), showing the ability to use PPG for AS change quantitative assessment.

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“…Increased brachial-ankle PWV is associated with impaired endothelial function in patients with coronary heart disease [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Aortic and arterial pulse wave velocity in patients with coronary heart disease of different severity

Hlimonenko¹,

Meigas²,

Viigimaa³

et al. 2008

Estonian J. Eng.

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The objective of the present study was to compare aortic and arterial pulse wave velocity (PWV) in coronary heart disease (CHD) patients and healthy young volunteers. Signals were obtained from 28 subjects. Severe coronary heart disease was confirmed by coronary angiography. Aortic PWV was measured using the TENSIOMed Arteriograph. Four arterial PWVs were gathered using a PowerLab 4/20T. The major finding of this study was that patients with CHD had increased aortic PWV compared with healthy subjects (P < 0.01). It was also found that in the CHD group, aortic PWV had a positive correlation with arterial PWV 2 , PWV 3 and PWV 4 (P < 0.01). Our study showed that difference in aortic and arterial PWV between CHD patients with different atherosclerosis grade was not significant. Further PWV studies should be focused on patients with pronounced risk factors but without established cardiovascular disease that allow to select patients with early phase of atherosclerosis.

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Increased brachial-ankle pulse wave velocity is associated with impaired endothelial function in patients with coronary artery disease

Cited by 14 publications

References 18 publications

Vascular adaptations to hypobaric hypoxic training in postmenopausal women

Vascular adaptations to hypobaric hypoxic training in postmenopausal women

Usability of photoplethysmography method in estimation of conduit artery stiffness

Aortic and arterial pulse wave velocity in patients with coronary heart disease of different severity

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