Increased blood levels of inflammatory cytokines CRP, TNF-α, CD40L, MCP-1 and Nitric Oxide in malignancy-associated thrombosis and their modulation by a low molecular weight heparin, Enoxaparin

Improvement of late life depression after therapeutic enoxaparin: two case reports

“…However, enoxaparin has previously been observed to have immune-modulating effects by inhibiting the proinflammatory cytokine TNF-α. 17,18 The cytokine hypothesis of major depression therefore offers an alternate mechanism by which enoxaparin could improve depression. The cytokine hypothesis proposes a role of elevated levels of pro-inflammatory cytokines in the development of depression.…”