Increased Bile Acids and FGF-19 after Sleeve Gastrectomy and Roux-en-Y Gastric Bypass Correlate with Improvement in Type 2 Diabetes in a Randomized Trial
Abstract:Background: Sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB), are both effective bariatric procedures to treat type 2 diabetes (T2DM) and obesity. The contribution of changes in bile acids (BAs) and fibroblast growth factor19 (FGF-19) to such metabolic improvements is unclear.
Methods: We examined associations between changes in BAs, FGF-19 (fasting and prandial), with changes in body weight, glycemia and other metabolic variables in 61 obese patients with T2DM before and one year aft… Show more
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